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abraxas 2, BRISC complex subunit

Summary

Gene Symbol

ABRAXAS2

Organism

Homo sapiens (human)

External Links

NCBI Gene

23172

PubChem

23172

Alliance of Genome Resources

HGNC:28975

Annotation

Keyword

3D-structure
Coiled coil
Cytoskeleton
Microtubule
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q15018	Abraxas brother protein 1 Protein FAM175B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
response to ischemia	IMP	21195082
mitotic cell cycle	IMP	26195665
protein K63-linked deubiquitination	IMP	24075985 26195665
attachment of spindle microtubules to kinetochore	IBA IMP	26195665
cell division	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

cell cycle [inference]

mitotic cell cycle

cell cycle process [inference]

spindle organization [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

response to stimulus [inference]

response to stress [inference]

response to ischemia

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
microtubule
midbody	IDA	26195665
BRISC complex	IDA	19214193 24075985
microtubule minus-end	IDA	26195665
spindle pole

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

BRISC complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

spindle pole centrosome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

microtubule end [inference]

microtubule minus-end

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19615732 26195665 32296183 33961781 37398436
microtubule binding	IBA IDA	26195665
polyubiquitin modification-dependent protein binding	IBA IDA	19261749

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

modification-dependent protein binding [inference]

polyubiquitin modification-dependent protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
microtubule binding
mitotic spindle assembly
polyubiquitin modification-dependent protein binding

Displaying 1 entry
InterPro
FAM175 family

Ortholog

Displaying entries **41 - 50** of 62 in total

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Species	Gene ID	Orthologous MAtrix
Erinaceus europaeus	103110511	ERIEU03802
Carlito syrichta	103264805	CARSF08507
Ursus maritimus	103659466	URSMA04332
Pteropus vampyrus	105295686	PTEVA05205
Macaca nemestrina	105470188	MACNE26730
Propithecus coquereli	105808718	PROCO14744
Microcebus murinus	105880358	MICMU11395
Dipodomys ordii	105989716	DIPOR13076
Equus asinus asinus	106841601	EQUAS19593
Rhinopithecus bieti	108519596	RHIBE02885