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fms related receptor tyrosine kinase 3

Summary

Gene Symbol

FLT3

Organism

Homo sapiens (human)

External Links

NCBI Gene

2322

PubChem

2322

Alliance of Genome Resources

HGNC:3765

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Disease variant
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Host-virus interaction
Immunoglobulin domain
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P36888	FL cytokine receptor Fetal liver kinase-2 Fms-like tyrosine kinase 3 Stem cell tyrosine kinase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	TAS	19549778
common myeloid progenitor cell proliferation	ISS
leukocyte homeostasis	ISS
animal organ regeneration	IEA
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	TAS	12951584

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

lymphocyte proliferation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

lymphocyte proliferation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

vascular endothelial growth factor signaling pathway

cytokine-mediated signaling pathway

cell population proliferation [inference]

common myeloid progenitor cell proliferation

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation [inference]

myeloid progenitor cell differentiation

lymphoid progenitor cell differentiation [inference]

pro-B cell differentiation

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

dendritic cell differentiation

cell development [inference]

hemopoiesis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

lymphocyte proliferation

multicellular organism development

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis

developmental process [inference]

anatomical structure development [inference]

multicellular organism development

regeneration [inference]

animal organ regeneration

cell development [inference]

hemopoiesis

animal organ development [inference]

animal organ regeneration

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation [inference]

myeloid progenitor cell differentiation

lymphoid progenitor cell differentiation [inference]

pro-B cell differentiation

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

dendritic cell differentiation

cell development [inference]

hemopoiesis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to organonitrogen compound

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to cytokine [inference]

cellular response to cytokine stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to nitrogen compound [inference]

response to organonitrogen compound

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

vascular endothelial growth factor signaling pathway

cytokine-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of MAP kinase activity

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
receptor complex	IBA
endoplasmic reticulum lumen	IEA
plasma membrane	IBA TAS
endoplasmic reticulum	IDA
endosome membrane	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

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GO Term	Evidence Code	PMID
protein binding	IPI	16982329 20098747 23246379 24525236 27458164 28086240
vascular endothelial growth factor receptor activity	TAS	8394751
protein-containing complex binding	IEA
cytokine receptor activity	ISS
transmembrane receptor protein tyrosine kinase activity	IBA TAS	19549778

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

binding [inference]

protein binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear glucocorticoid receptor binding

growth factor binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

immune receptor activity [inference]

cytokine receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

kinase regulator activity [inference]

phosphatidylinositol 3-kinase regulator activity [inference]

phosphatidylinositol 3-kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

vascular endothelial growth factor receptor

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
growth factor binding
metal ion binding
nucleotide binding
positive regulation of cell migration
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway

Displaying entries **1 - 10** of 11 in total

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InterPro
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyrosine-protein kinase, active site
Tyrosine-protein kinase, catalytic domain

Disease

Disease Ontology

Displaying entries **1 - 10** of 13 in total

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DO ID	Disease Name	Source
DOID:0050458	juvenile myelomonocytic leukemia	Alliance of Genome Resources
DOID:0050861	colorectal adenocarcinoma	Alliance of Genome Resources
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources
DOID:0080630	B-lymphoblastic leukemia/lymphoma	Alliance of Genome Resources
DOID:0081082	acute myelomonocytic leukemia	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:162	cancer	Alliance of Genome Resources
DOID:305	carcinoma	Alliance of Genome Resources
DOID:4971	myelofibrosis	Alliance of Genome Resources
DOID:585	nephrolithiasis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	14255	MGI:95559	MOUSE44149
Drosophila melanogaster	34127	FB:FBgn0032006
Rattus norvegicus	140635	RGD:61308	RATNO06105
Caenorhabditis elegans	173049	WB:WBGene00012270
Caenorhabditis elegans	174501	WB:WBGene00011168
Caenorhabditis elegans	175182	WB:WBGene00006894
Caenorhabditis elegans	180032	WB:WBGene00002211
Caenorhabditis elegans	186632	WB:WBGene00006897
Caenorhabditis elegans	187740	WB:WBGene00011169
Caenorhabditis elegans	191737	WB:WBGene00003862

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements