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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fms related receptor tyrosine kinase 3 ligand
Summary
- Gene Symbol
-
- FLT3LG
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| embryonic hemopoiesis | ||
| signal transduction |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| plasma membrane | ||
| extracellular region | ||
| cell surface | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| signaling receptor binding | ||
| cytokine activity | ||
| receptor tyrosine kinase binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- fms-related tyrosine kinase 3 ligand
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| kinase activity |
| phosphorylation |
| positive regulation of cell population proliferation |
| receptor tyrosine kinase binding |
| InterPro |
|---|
| Flt3 ligand |
| Four-helical cytokine-like, core |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12449 | aplastic anemia | |
| DOID:13636 | Fanconi anemia | |
| DOID:1520 | colon carcinoma | |
| DOID:1793 | pancreatic cancer | |
| DOID:3068 | glioblastoma | |
| DOID:3070 | high grade glioma | |
| DOID:4971 | myelofibrosis | |
| DOID:9538 | multiple myeloma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14256 | MGI:95560 | MOUSE53972 | ||
| 282233 | BOVIN11521 | |||
| 317646 | RATNO18426 | |||
| 493796 | FELCA34745 | |||
| 100439816 | 9601_0:004835 | PONAB14348 | ||
| 100610021 | 9598_0:004f5d | PANTR18924 | ||
| 100723994 | CAVPO19359 | |||
| 100773162 | CRIGR18304 | |||
| 100987536 | 9597_0:0049c2 | |||
| 101007432 | PAPAN22342 |
