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SMG6 nonsense mediated mRNA decay factor

Summary

Gene Symbol

SMG6

Organism

Homo sapiens (human)

External Links

NCBI Gene

23293

PubChem

23293

Alliance of Genome Resources

HGNC:17809

JoGo

SMG6

TogoVar

SMG6

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Cytoplasm
DNA-binding
Endonuclease
Manganese
Metal-binding
Methylation
Nonsense-mediated mRNA decay
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Telomere

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86US8	Ever shorter telomeres 1A Nonsense mediated mRNA decay factor SMG6 Smg-6 homolog hSmg5/7a

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS	16488880
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IMP	18974281 19060897 20930030
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IBA
mRNA export from nucleus	TAS	16488880
regulation of telomere maintenance	IMP	12699629 17916692

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA metabolic process [inference]

regulation of telomere maintenance

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of telomere capping [inference]

negative regulation of telomere capping

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA metabolic process [inference]

regulation of telomere maintenance

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of telomere capping [inference]

negative regulation of telomere capping

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA metabolic process [inference]

regulation of telomere maintenance

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of telomere capping [inference]

negative regulation of telomere capping

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA metabolic process [inference]

regulation of telomere maintenance

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of telomere capping [inference]

negative regulation of telomere capping

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA metabolic process [inference]

regulation of telomere maintenance

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of telomere capping [inference]

negative regulation of telomere capping

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of chromosome organization [inference]

regulation of telomere maintenance

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

regulation of telomere capping [inference]

negative regulation of telomere capping

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere capping

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GO Term	Evidence Code	PMID
chromosome, telomeric region	IEA
nucleus	IDA	14636577
telomerase holoenzyme complex	TAS	12699629
telomerase holoenzyme complex	IBA
nucleolus	IDA	12676087

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

catalytic complex [inference]

telomerase holoenzyme complex

ribonucleoprotein complex [inference]

telomerase holoenzyme complex

cellular anatomical entity [inference]

cytoplasm

microtubule organizing center [inference]

ciliary basal body

cytosol

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

chromosomal region [inference]

chromosome, telomeric region

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GO Term	Evidence Code	PMID
RNA binding	IPI	17940095
RNA endonuclease activity	TAS
RNA endonuclease activity	IDA	19060897
RNA endonuclease activity	IMP	18974281
protein binding	IPI	12699629 20930030 21145460 25220460 32296183 32814053

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

RNA endonuclease activity

RNA nuclease activity [inference]

RNA endonuclease activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA endonuclease activity

binding [inference]

protein binding

enzyme binding [inference]

DNA polymerase binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

sequence-specific DNA binding [inference]

telomeric DNA binding

RNA binding

telomerase RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Telomerase-binding protein est1a

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
telomerase RNA binding
telomeric DNA binding

Displaying **all 6** entries
InterPro
DNA/RNA-binding domain, Est1-type
Est1/Ebs1-like
PIN domain
PIN-like domain superfamily
Telomerase activating protein Est1-like, N-terminal
Tetratricopeptide-like helical domain superfamily

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements