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Sad1 and UNC84 domain containing 1

Summary

Gene Symbol

SUN1

Organism

Homo sapiens (human)

External Links

NCBI Gene

23353

PubChem

23353

Alliance of Genome Resources

HGNC:18587

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Disulfide bond
Isopeptide bond
Meiosis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Signal-anchor
Spermatogenesis
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8I5G938
O94901	Protein unc-84 homolog A Sad1/unc-84 protein-like 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nuclear matrix anchoring at nuclear membrane	IDA	18396275
centrosome localization	IEA
response to mechanical stimulus	IEA
spermatogenesis	IEA
meiotic attachment of telomere to nuclear envelope	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

cell cycle process [inference]

chromosome attachment to the nuclear envelope [inference]

meiotic attachment of telomere to nuclear envelope

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

meiotic attachment of telomere to nuclear envelope

cellular localization [inference]

intracellular transport [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

nuclear matrix anchoring at nuclear membrane

microtubule organizing center localization [inference]

centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear matrix organization [inference]

nuclear matrix anchoring at nuclear membrane

chromosome organization [inference]

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

meiotic attachment of telomere to nuclear envelope

multicellular organismal process [inference]

ossification

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

response to stimulus [inference]

response to external stimulus [inference]

response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

microtubule-based transport [inference]

transport along microtubule [inference]

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

establishment of organelle localization [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

nuclear matrix anchoring at nuclear membrane

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

nuclear matrix anchoring at nuclear membrane

organelle localization [inference]

chromosome localization [inference]

chromosome attachment to the nuclear envelope [inference]

meiotic attachment of telomere to nuclear envelope

nucleus localization [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

establishment of organelle localization [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule [inference]

nuclear migration along microtubule [inference]

nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration

microtubule organizing center localization [inference]

centrosome localization

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nuclear inner membrane	IEA
nuclear membrane	IDA
intracellular membrane-bounded organelle	IDA
chromosome, telomeric region	IEA
meiotic nuclear membrane microtubule tethering complex	IBA IDA	18396275

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

nuclear membrane protein complex [inference]

nuclear membrane microtubule tethering complex [inference]

meiotic nuclear membrane microtubule tethering complex

nuclear protein-containing complex [inference]

nuclear membrane protein complex [inference]

nuclear membrane microtubule tethering complex [inference]

meiotic nuclear membrane microtubule tethering complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

nuclear inner membrane

nuclear membrane

nuclear inner membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

chromosomal region [inference]

chromosome, telomeric region

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	18396275 22632968 24375709 28716842 33393904 33961781
cytoskeleton-nuclear membrane anchor activity	IDA	18396275
identical protein binding	IPI	22632968 33393904
protein-membrane adaptor activity	IBA
lamin binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

protein-membrane adaptor activity

cytoskeleton-nuclear membrane anchor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sperm-associated antigen 4

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
protein-membrane adaptor activity

Displaying **all 2** entries
InterPro
SUN domain-containing protein 1-5
SUN domain

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	35594		FB:FBgn0265003
Mus musculus	77053		MGI:1924303	MOUSE46865
Rattus norvegicus	360773		RGD:1359142	RATNO05554
Pan troglodytes	472263	9598_0:002067		PANTR39575
Canis lupus familiaris	480806			CANLF16343
Danio rerio	553188		ZFIN:ZDB-GENE-050522-551	DANRE30880
Macaca mulatta	708786			MACMU32364
Xenopus laevis	733164		Xenbase:XB-GENE-995956
Danio rerio	751759		ZFIN:ZDB-GENE-060825-353
Monodelphis domestica	100021066			MONDO28235