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VPS8 subunit of CORVET complex

Summary

Gene Symbol

VPS8

Organism

Homo sapiens (human)

External Links

NCBI Gene

23355

PubChem

23355

Alliance of Genome Resources

HGNC:29122

JoGo

VPS8

TogoVar

VPS8

Annotation

Keyword

Alternative splicing
Endosome
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome
WD repeat
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8N3P4
B3KPR6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein targeting to vacuole	IBA
endosomal vesicle fusion	NAS	31092635
endosomal vesicle fusion	IMP	25266290
endosomal vesicle fusion	IBA
regulation of SNARE complex assembly	NAS	31092635

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle fusion [inference]

endosomal vesicle fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

regulation of SNARE complex assembly

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

regulation of SNARE complex assembly

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
early endosome	IDA	25266290
early endosome	IBA
late endosome	IBA
HOPS complex	IBA
CORVET complex	NAS	31092635

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

HOPS complex

vesicle tethering complex [inference]

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25266290 33961781 35271311
zinc ion binding	IEA
metal ion binding

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Vacuolar sorting-associated 8

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
endosomal vesicle fusion
protein targeting to vacuole

Displaying **all 4** entries
InterPro
Vacuolar protein sorting-associated protein 8, central domain
Vacuolar protein sorting-associated protein Vps41/Vps8
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily