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Ecm29 proteasome adaptor and scaffold

Summary

Gene Symbol

ECPAS

Organism

Homo sapiens (human)

External Links

NCBI Gene

23392

PubChem

23392

Alliance of Genome Resources

HGNC:29020

JoGo

ECPAS

TogoVar

ECPAS

Annotation

Keyword

Acetylation
Alternative splicing
Cytoplasmic vesicle
Cytoskeleton
Endoplasmic reticulum
Endosome
Isopeptide bond
Nucleus
Phosphoprotein
Proteasome
Proteomics identification
Reference proteome
Repeat
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q5VYK3	Ecm29 proteasome adapter and scaffold Proteasome-associated protein ECM29 homolog
A0AAA9X0G7	Proteasome-associated protein ECM29 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ERAD pathway	IMP	15496406
ERAD pathway	IBA
proteasome assembly	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

proteasome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

proteasome assembly

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
proteasome complex	IEA
nucleus	IDA	15496406
nucleus	IBA
nucleoplasm	IDA
cytoplasm	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

proteasome complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

proteasome complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

late endosome

multivesicular body

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

endocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

late endosome

multivesicular body

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

late endosome

multivesicular body

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

endocytic vesicle

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 32296183
molecular adaptor activity	IBA
proteasome binding	IDA	15496406

GO Hierarchy

molecular function

binding [inference]

protein binding

protein-containing complex binding [inference]

proteasome binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ECM29

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying 1 entry
Gene Ontology
proteasome assembly

Displaying **all 3** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Proteasome component Ecm29

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Last updated: December 8, 2025

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Acknowledgements