sirtuin 1
| GO Term | Evidence Code | PMID |
|---|---|---|
| single strand break repair | ||
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| rDNA heterochromatin formation | ||
| rDNA heterochromatin formation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| p53 binding | ||
| p53 binding | ||
| transcription coactivator activity | ||
| transcription corepressor activity |
| Gene Ontology |
|---|
| NAD+ binding |
| metal ion binding |
| transferase activity |
| InterPro |
|---|
| DHS-like NAD/FAD-binding domain superfamily |
| Sirtuin family, catalytic core domain |
| Sirtuin family |
| Sirtuin, catalytic core small domain superfamily |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12858 | Huntington's disease |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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