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TNF receptor superfamily member 13B

Summary

Gene Symbol

TNFRSF13B

Organism

Homo sapiens (human)

External Links

NCBI Gene

23495

PubChem

23495

Alliance of Genome Resources

HGNC:18153

Annotation

Keyword

3D-structure
Adaptive immunity
Alternative splicing
Disease variant
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Repeat
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O14836	Transmembrane activator and CAML interactor
Q4ACX1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	TAS	9311921
hematopoietic progenitor cell differentiation	IBA
adaptive immune response	IEA
B cell homeostasis	IBA
negative regulation of B cell proliferation	IBA

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

immune response [inference]

adaptive immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

response to stimulus [inference]

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	10801128 10880535 10956646 20676093 25416956 25910212 32296183
signaling receptor activity	TAS	9311921

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Tumor necrosis factor receptor superfamily member 13B

Functional Category

L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
B cell homeostasis
hematopoietic progenitor cell differentiation
negative regulation of B cell proliferation

Displaying **all 2** entries
InterPro
TACI, cysteine-rich domain
Tumour necrosis factor receptor 13B

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0081145	common variable immunodeficiency 2	Alliance of Genome Resources
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 33 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	57916		MGI:1889411	MOUSE04089
Macaca mulatta	574200			MACMU13625
Bos taurus	617948			BOVIN13008
Pan troglodytes	744388	9598_0:004650		PANTR14712
Equus caballus	100051166			HORSE04342
Ornithorhynchus anatinus	100080237			ORNAN16950
Taeniopygia guttata	100228892			TAEGU05090
Pongo abelii	100462060	9601_0:0042b3		PONAB11299
Ailuropoda melanoleuca	100477179			AILME02772
Cavia porcellus	100726640			CAVPO18655