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protein tyrosine phosphatase receptor type Q

Summary

Gene Symbol

Ptprq

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

237523

PubChem

237523

Alliance of Genome Resources

MGI:1096349

Annotation

Keyword

Cell membrane
Cell projection
Deafness
Glycoprotein
Protein phosphatase
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P0C5E4	Receptor-type tyrosine-protein phosphatase Q

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
vestibular receptor cell morphogenesis	IMP	22357859
inner ear morphogenesis	IMP	14534255
hematopoietic progenitor cell differentiation	IMP	24029230
detection of mechanical stimulus involved in sensory perception of sound	IBA IMP	22357859
protein dephosphorylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

neuromuscular process [inference]

neuromuscular process controlling balance

detection of mechanical stimulus involved in sensory perception of sound

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

cell morphogenesis involved in neuron differentiation [inference]

vestibular receptor cell morphogenesis

embryonic morphogenesis [inference]

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to abiotic stimulus [inference]

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of fat cell differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

regulation of fat cell differentiation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
apical plasma membrane	IDA	24285636
receptor complex	IBA
basal plasma membrane	IEA
stereocilium bundle	IDA	22357859
stereocilium base	IDA	24285636 37952086

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

cluster of actin-based cell projections [inference]

stereocilium bundle

stereocilium base

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	37952086
protein tyrosine phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

phosphatidylinositol phosphatase PTPRQ

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
X: Mobilome: prophages, transposons

Displaying **all 4** entries
Gene Ontology
dephosphorylation
hydrolase activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080269	autosomal dominant nonsyndromic deafness 73	Alliance of Genome Resources
DOID:0110529	autosomal recessive nonsyndromic deafness 84A	Alliance of Genome Resources
DOID:934	viral infectious disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23628		HGNC:9679
Drosophila melanogaster	32976		FB:FBgn0043903
Rattus norvegicus	360417	10116_1:0028c6	RGD:620779	RATNO36948
Homo sapiens	374462			HUMAN14479
Danio rerio	555426		ZFIN:ZDB-GENE-050419-183
Macaca mulatta	697153			MACMU03435
Pan troglodytes	745373			PANTR06497
Monodelphis domestica	100019595			MONDO33707
Ornithorhynchus anatinus	100073681			ORNAN06301
Oryctolagus cuniculus	100351401			RABIT10588

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements