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sarcoglycan, beta (dystrophin-associated glycoprotein)

Summary

Gene Symbol

Sgcb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

24051

PubChem

24051

Alliance of Genome Resources

MGI:1346523

Annotation

Keyword

Cell membrane
Cytoskeleton
Disulfide bond
Glycoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P82349	43 kDa dystrophin-associated glycoprotein

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
vascular associated smooth muscle cell development	IMP	10678176
response to glucose	IMP	19494113
muscle cell development	IMP	10678176
membrane organization	TAS	12189167
gene expression	IMP	19494113

GO Hierarchy

biological process

metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell development [inference]

muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell development [inference]

muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

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GO Term	Evidence Code	PMID
cytoplasm	IEA
plasma membrane	IDA TAS	10448073 10481911 16524571 17164264
sarcoglycan complex	IBA IDA	16524571 19494113
sarcolemma	IBA IDA	10678176
dystrophin-associated glycoprotein complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

glycoprotein complex [inference]

dystrophin-associated glycoprotein complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

sarcolemma

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	16524571

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Beta-sarcoglycan

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis

Displaying 1 entry
Gene Ontology
muscle organ development

Displaying **all 2** entries
InterPro
Beta-sarcoglycan
Sarcoglycan complex subunit protein

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110279	autosomal recessive limb-girdle muscular dystrophy type 2E	Alliance of Genome Resources
DOID:9884	muscular dystrophy	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6443		HGNC:10806	HUMAN75546
Drosophila melanogaster	41525		FB:FBgn0038042
Caenorhabditis elegans	186816		WB:WBGene00019277
Pan troglodytes	461332			PANTR33991
Danio rerio	559788		ZFIN:ZDB-GENE-030131-6695	DANRE19811
Canis lupus familiaris	611066			CANLF03386
Rattus norvegicus	680229	10116_1:004304	RGD:1594202	RATNO07887
Macaca mulatta	698988			MACMU36111
Macaca mulatta	702684			MACMU36111
Oryctolagus cuniculus	100009208			RABIT08058

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements