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Repository for lectin-assisted multimodality data
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MIRAGE
CF transmembrane conductance regulator
Summary
- Gene Symbol
-
- Cftr
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Chloride channel
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Isomerase
- Nucleus
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cholesterol biosynthetic process | ||
| negative regulation of vascular associated smooth muscle cell apoptotic process | ||
| vasodilation | ||
| cellular response to anoxia | ||
| positive regulation of cyclic nucleotide-gated ion channel activity |
GO Hierarchy
- regulation of membrane depolarization
biological process
metabolic process [inference]
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of cellular localization [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ABC-type transporter activity | ||
| chloride channel activity | ||
| chloride transmembrane transporter activity | ||
| ATP binding | ||
| isomerase activity |
GO Hierarchy
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050127 | sinusitis | |
| DOID:0060643 | primary sclerosing cholangitis | |
| DOID:0080526 | bronchiectasis 1 | |
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:0111862 | congenital bilateral absence of vas deferens | |
| DOID:0111864 | autosomal recessive congenital bilateral absence of vas deferens | |
| DOID:10211 | cholelithiasis | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10808 | gastric ulcer | |
| DOID:11132 | prostatic hypertrophy |
