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dopamine receptor D2
Summary
- Gene Symbol
-
- Drd2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor signaling pathway | ||
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway | ||
| negative regulation of adenylate cyclase activity | ||
| adenylate cyclase-inhibiting dopamine receptor signaling pathway | ||
| adenylate cyclase-inhibiting dopamine receptor signaling pathway |
GO Hierarchy
- pigmentation
biological process
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of secretion [inference]
negative regulation of transport [inference]
regulation of amine transport [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
negative regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| presynaptic membrane | ||
| presynaptic membrane | ||
| dendritic spine | ||
| perikaryon | ||
| axon terminus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| dopamine neurotransmitter receptor activity, coupled via Gi/Go | ||
| dopamine neurotransmitter receptor activity, coupled via Gi/Go | ||
| dopamine neurotransmitter receptor activity, coupled via Gi/Go | ||
| G-protein alpha-subunit binding | ||
| G protein-coupled receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0080855 | Parkinsonism | |
| DOID:5425 | ovarian hyperstimulation syndrome | |
| DOID:9975 | cocaine dependence |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 114585861 | PODMU12058 | ||
| 115052814 | ECHNA07033 | ||
| 115162927 | SALTR97724 | ||
| 115205882 | SALTR110964 | ||
| 115400976 | SALFA46689 | ||
| 115528771 | GADMO19406 | ||
| 115572610 | SPAAU17776 | ||
| 115616396 | STRHB18243 | ||
| 116455689 | CORMO12224 | ||
| 116820850 | CHEAB19077 |
