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leucine rich repeat and fibronectin type III, extracellular 1

Summary

Gene Symbol

Elfn1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

243312

PubChem

243312

Alliance of Genome Resources

MGI:2442479

Annotation

Keyword

Cell projection
Glycoprotein
Leucine-rich repeat
Phosphoprotein
Protein phosphatase inhibitor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8C8T7	Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1 Protein phosphatase 1 regulatory subunit 28

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
synapse assembly	IMP	36179691
establishment of protein localization	IDA	32879010
synapse organization	IMP	23042292
synaptic membrane adhesion	IDA IEP IMP	25047565
visual perception	IMP	36179691

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization

synapse assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization

establishment of localization [inference]

establishment of protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
extracellular matrix	IBA
axon terminus	IDA	36179691
postsynaptic density membrane	IDA IEP IMP	25047565
neuron projection terminus	IDA	32879010
dendrite	IDA	23042292

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

neuron projection terminus

axon terminus

presynapse [inference]

axon terminus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32879010
protein phosphatase inhibitor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

phosphatase regulator activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

protein phosphatase regulator activity [inference]

protein phosphatase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein ELFN1

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Cysteine-rich flanking region, C-terminal
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **127** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	171635		WB:WBGene00006593
Rattus norvegicus	288512	10116_1:003fc6	RGD:1308787	RATNO05171
Homo sapiens	392617		HGNC:33154	HUMAN87601
Danio rerio	562570		ZFIN:ZDB-GENE-120927-2
Bos taurus	618774			BOVIN21050
Macaca mulatta	697716			MACMU32670
Pan troglodytes	737447			PANTR39584
Monodelphis domestica	100029173			MONDO28417
Ornithorhynchus anatinus	100083034			ORNAN15756
Danio rerio	100144401		ZFIN:ZDB-GENE-080327-21

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements