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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate ionotropic receptor NMDA type subunit 2D
Summary
- Gene Symbol
-
- Grin2d
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Magnesium
- Methylation
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q62645 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| synaptic transmission, glutamatergic | ||
| regulation of neuronal synaptic plasticity | ||
| long-term synaptic potentiation | ||
| detection of mechanical stimulus involved in sensory perception of pain | ||
| adult locomotory behavior |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| postsynaptic density membrane | ||
| NMDA selective glutamate receptor complex | ||
| endoplasmic reticulum membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | ||
| glutamate-gated calcium ion channel activity | ||
| NMDA glutamate receptor activity | ||
| glutamate binding |
GO Hierarchy
molecular function
transporter activity [inference]
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Ionotropic glutamate receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060037 | developmental disorder of mental health | |
| DOID:0080456 | developmental and epileptic encephalopathy 46 | |
| DOID:1826 | epilepsy | |
| DOID:5419 | schizophrenia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 116892121 | 10117_0:001187 | |||
| 117706708 | 61156_0:0001dd | |||
| 118575416 | 38674_0:004f9f | |||
| 118579159 | 38674_0:0000eb | |||
| 119802465 | 1047088_0:0042ec | |||
| 121451796 | 111838_0:0000ad | |||
| 122125845 | 105255_0:003b60 | |||
| 124107939 | 9995_0:002e54 | |||
| 124966828 | 30640_0:0045df | |||
| 125338675 | 214514_0:0040fa |
