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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate ionotropic receptor NMDA type subunit 2D
Summary
- Gene Symbol
-
- Grin2d
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Magnesium
- Methylation
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q62645 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to L-glutamate | ||
| regulation of presynaptic membrane potential |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| postsynaptic density membrane | ||
| NMDA selective glutamate receptor complex | ||
| endoplasmic reticulum membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | ||
| glutamate-gated calcium ion channel activity | ||
| NMDA glutamate receptor activity | ||
| glutamate binding |
GO Hierarchy
molecular function
transporter activity [inference]
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Ionotropic glutamate receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060037 | developmental disorder of mental health | |
| DOID:0080456 | developmental and epileptic encephalopathy 46 | |
| DOID:1826 | epilepsy | |
| DOID:5419 | schizophrenia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 107151575 | 9994_0:0040af | |||
| 110219850 | PHACI18905 | |||
| 110298186 | 10089_0:0020eb | |||
| 110319211 | 10093_0:00040b | |||
| 113194982 | 9999_0:0031ba | |||
| 114041905 | VOMUR30697 | |||
| 114079233 | 93162_0:00438e | |||
| 114640022 | 491861_0:003cd0 | |||
| 114684718 | 10041_0:0004dd | |||
| 116102223 | 35658_0:00279a |
