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ectodysplasin A2 receptor

Summary

Gene Symbol

Eda2r

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

245527

PubChem

245527

Alliance of Genome Resources

MGI:2442860

Annotation

Keyword

Developmental protein
Differentiation
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3KP88
Q8BX35	X-linked ectodysplasin-A2 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
intrinsic apoptotic signaling pathway by p53 class mediator	IGI	20434500
tumor necrosis factor-mediated signaling pathway	IEA
programmed cell death	RCA	12819136
cytokine-mediated signaling pathway	ISO
cell differentiation	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

tumor necrosis factor-mediated signaling pathway

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

cell death [inference]

programmed cell death

cellular developmental process [inference]

cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

tumor necrosis factor-mediated signaling pathway

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of JNK cascade

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IBA IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
tumor necrosis factor receptor activity	IEA
signaling receptor activity	IBA
transmembrane signaling receptor activity	ISO ISS

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

death receptor activity [inference]

tumor necrosis factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

tumor necrosis factor receptor superfamily member 27

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
Gene Ontology
positive regulation of JNK cascade
positive regulation of canonical NF-kappaB signal transduction
tumor necrosis factor-mediated signaling pathway

Displaying **all 4** entries
InterPro
TNFR/NGFR cysteine-rich region
Tumor necrosis factor receptor 27, N-terminal
Tumor necrosis factor receptor superfamily member 19/27/EDAR
Tumour necrosis factor receptor 27

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	60401		HGNC:17756	HUMAN101059
Rattus norvegicus	296872	10116_1:00544a	RGD:1564025	RATNO45386
Pan troglodytes	473648			PANTR46173
Macaca mulatta	710244			MACMU47628
Callithrix jacchus	100400510			CALJA46884
Pongo abelii	100435021			PONAB37180
Ailuropoda melanoleuca	100482463			AILME03647
Xenopus tropicalis	100493834		Xenbase:XB-GENE-940659
Nomascus leucogenys	100603908			NOMLE38147
Cavia porcellus	100713249	10141_0:000902