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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neuroligin 3
Summary
- Gene Symbol
-
- Nlgn3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Cell membrane
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Signal
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8BYM5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuron cell-cell adhesion | ||
| positive regulation of synaptic vesicle clustering | ||
| regulation of long-term synaptic potentiation | ||
| excitatory postsynaptic potential | ||
| inhibitory postsynaptic potential |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| inhibitory synapse | ||
| postsynaptic membrane | ||
| endocytic vesicle | ||
| presynapse |
|
|
| postsynaptic specialization membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| neurexin family protein binding | ||
| signaling receptor activity | ||
| scaffold protein binding | ||
| cell adhesion molecule binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroligin-3
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase type B, conserved site |
| Carboxylesterase, type B |
| Neuroligin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:11446 | sciatic neuropathy | |
| DOID:12849 | autistic disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 118573897 | 38674_0:004cab | |||
| 118889058 | BALMU19352 | |||
| 119805070 | 1047088_0:004fe5 | |||
| 121443324 | 111838_0:005cde | |||
| 121444957 | 111838_0:006118 | |||
| 122120659 | 105255_0:0030f8 | |||
| 124108585 | 9995_0:002fcc | |||
| 124972478 | 30640_0:0051e4 | |||
| 125343241 | 214514_0:004da9 | |||
| 125389506 | 447135_0:003d85 |
