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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neuroligin 3
Summary
- Gene Symbol
-
- Nlgn3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Cell membrane
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Signal
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8BYM5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of dendritic spine development | ||
| regulation of respiratory gaseous exchange by nervous system process | ||
| postsynaptic membrane assembly | ||
| long-term synaptic potentiation | ||
| negative regulation of dendritic spine morphogenesis |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| inhibitory synapse | ||
| postsynaptic membrane | ||
| endocytic vesicle | ||
| presynapse |
|
|
| postsynaptic specialization membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| neurexin family protein binding | ||
| signaling receptor activity | ||
| scaffold protein binding | ||
| cell adhesion molecule binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroligin-3
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase type B, conserved site |
| Carboxylesterase, type B |
| Neuroligin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:11446 | sciatic neuropathy | |
| DOID:12849 | autistic disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101679763 | MUSPF02836 | |||
| 101715602 | 10181_0:004934 | |||
| 101811330 | FICAL07026 | |||
| 101824900 | 10036_0:00114c | |||
| 101879186 | MELUD08576 | |||
| 101932106 | CHRPI11818 | |||
| 101960249 | 43179_0:0001eb | ICTTR07281 | ||
| 101986965 | 79684_0:002c2e | |||
| 102003537 | 34839_0:003519 | CHILA17546 | ||
| 102168988 | CAPHI30646 |
