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defensin beta 130A

Summary

Gene Symbol

DEFB130A

Organism

Homo sapiens (human)

External Links

NCBI Gene

245940

PubChem

245940

Alliance of Genome Resources

HGNC:18107

JoGo

DEFB130A

TogoVar

DEFB130A

Annotation

Keyword

Antibiotic
Defensin
Disulfide bond
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P0DP74	Beta-defensin 130 Beta-defensin 30 Defensin, beta 130

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
defense response to bacterium	IBA
defense response to protozoan	IMP	28181499
positive chemotaxis	IEA
cytolysis by host of symbiont cells	IMP	28181499
cell chemotaxis	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

cell killing [inference]

killing of cells of another organism [inference]

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

cell motility [inference]

cell migration [inference]

cell chemotaxis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with symbiont [inference]

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

response to other organism [inference]

response to protozoan [inference]

defense response to protozoan

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism [inference]

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to protozoan [inference]

defense response to protozoan

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to protozoan [inference]

defense response to protozoan

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IBA
cytosol	IDA	28181499

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
CCR6 chemokine receptor binding	IBA
chemoattractant activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding [inference]

CCR chemokine receptor binding [inference]

CCR6 chemokine receptor binding

cytokine receptor binding [inference]

chemokine receptor binding [inference]

CCR chemokine receptor binding [inference]

CCR6 chemokine receptor binding

receptor ligand activity [inference]

chemoattractant activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

chemoattractant activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

chemoattractant activity

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026

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