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nitric oxide synthase 1

Summary

Gene Symbol

Nos1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24598

PubChem

24598

Alliance of Genome Resources

RGD:3184

Annotation

Keyword

3D-structure
Alternative splicing
Calmodulin-binding
Cell membrane
Cell projection
Direct protein sequencing
FAD
FMN
Heme
NADP
Oxidoreductase
Phosphoprotein
Reference proteome
Synapse
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P29476	Constitutive NOS NC-NOS NOS type I Neuronal NOS Nitric oxide synthase, brain Peptidyl-cysteine S-nitrosylase NOS1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 73 in total

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GO Term	Evidence Code	PMID
response to hypoxia	ISO
response to hypoxia	IEP	16276418 17442632
response to hypoxia	IEA
regulation of sodium ion transport	ISO
arginine catabolic process	IDA	1383204

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein nitrosylation [inference]

peptidyl-cysteine S-nitrosylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-cysteine S-nitrosylation

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process

nitric oxide biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

xenobiotic catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

xenobiotic metabolic process [inference]

xenobiotic catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

xenobiotic catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein nitrosylation [inference]

peptidyl-cysteine S-nitrosylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-cysteine S-nitrosylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nitrosylation [inference]

peptidyl-cysteine S-nitrosylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-cysteine S-nitrosylation

macromolecule modification [inference]

protein modification process [inference]

protein nitrosylation [inference]

peptidyl-cysteine S-nitrosylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-cysteine S-nitrosylation

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein nitrosylation [inference]

peptidyl-cysteine S-nitrosylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-cysteine S-nitrosylation

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

synaptic signaling by nitric oxide

trans-synaptic signaling by nitric oxide [inference]

retrograde trans-synaptic signaling by nitric oxide

trans-synaptic signaling [inference]

retrograde trans-synaptic signaling [inference]

retrograde trans-synaptic signaling by soluble gas [inference]

retrograde trans-synaptic signaling by nitric oxide

trans-synaptic signaling by soluble gas [inference]

retrograde trans-synaptic signaling by soluble gas [inference]

retrograde trans-synaptic signaling by nitric oxide

trans-synaptic signaling by nitric oxide [inference]

retrograde trans-synaptic signaling by nitric oxide

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

nitric oxide mediated signal transduction

nitric oxide-cGMP-mediated signaling pathway

cyclic-nucleotide-mediated signaling [inference]

cGMP-mediated signaling [inference]

nitric oxide-cGMP-mediated signaling pathway

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

xenobiotic metabolic process [inference]

xenobiotic catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

xenobiotic catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

reproductive process [inference]

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

vasodilation

behavior [inference]

adult behavior [inference]

behavioral response to cocaine

multicellular organismal response to stress

multi-multicellular organism process [inference]

female pregnancy

response to stimulus [inference]

response to stress [inference]

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to extracellular stimulus [inference]

response to nutrient levels

response to nutrient [inference]

response to vitamin [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to activity

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to monoamine [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to catecholamine [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to epinephrine [inference]

cellular response to epinephrine stimulus

response to peptide [inference]

response to peptide hormone

response to organic cyclic compound

response to vitamin E

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to catecholamine [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to epinephrine [inference]

cellular response to epinephrine stimulus

response to lipid [inference]

response to lipopolysaccharide

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to alcohol [inference]

response to ethanol

response to inorganic substance [inference]

response to metal ion [inference]

response to lead ion

response to nitric oxide

response to nicotine

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to monoamine [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to catecholamine [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to epinephrine [inference]

cellular response to epinephrine stimulus

response to peptide [inference]

response to peptide hormone

response to nitric oxide

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to oxygen-containing compound [inference]

response to catecholamine [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

response to epinephrine [inference]

cellular response to epinephrine stimulus

response to alcohol [inference]

response to ethanol

response to peptide [inference]

response to peptide hormone

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to monoamine stimulus [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to oxygen-containing compound [inference]

cellular response to catecholamine stimulus [inference]

cellular response to epinephrine stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

organic substance transport [inference]

calcium ion transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

synaptic signaling by nitric oxide

trans-synaptic signaling by nitric oxide [inference]

retrograde trans-synaptic signaling by nitric oxide

trans-synaptic signaling [inference]

retrograde trans-synaptic signaling [inference]

retrograde trans-synaptic signaling by soluble gas [inference]

retrograde trans-synaptic signaling by nitric oxide

trans-synaptic signaling by soluble gas [inference]

retrograde trans-synaptic signaling by soluble gas [inference]

retrograde trans-synaptic signaling by nitric oxide

trans-synaptic signaling by nitric oxide [inference]

retrograde trans-synaptic signaling by nitric oxide

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of iron ion transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of iron ion transport [inference]

negative regulation of iron ion transport [inference]

negative regulation of iron ion transmembrane transport

regulation of iron ion transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of iron ion transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of iron ion transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

regulation of secretion [inference]

regulation of peptide secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of iron ion transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter uptake [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of serotonin uptake [inference]

negative regulation of serotonin uptake

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of hepatic stellate cell contraction

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of iron ion transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of neurogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

nitric oxide mediated signal transduction

nitric oxide-cGMP-mediated signaling pathway

cyclic-nucleotide-mediated signaling [inference]

cGMP-mediated signaling [inference]

nitric oxide-cGMP-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of actin filament-based process [inference]

regulation of actin filament-based movement [inference]

regulation of hepatic stellate cell contraction [inference]

negative regulation of hepatic stellate cell contraction

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of iron ion transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of neurogenesis

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of iron ion transmembrane transport

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of hepatic stellate cell contraction

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of the force of heart contraction [inference]

positive regulation of the force of heart contraction

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis

regulation of biological quality [inference]

regulation of the force of heart contraction [inference]

positive regulation of the force of heart contraction

regulation of blood pressure [inference]

negative regulation of blood pressure

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

negative regulation of cytosolic calcium ion concentration

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

vasodilation

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity

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GO Term	Evidence Code	PMID
photoreceptor inner segment	IDA	17027776
nucleus	IDA	11590170 26607632
nucleus	IBA
nucleoplasm	ISO
nucleoplasm	IEA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

sarcolemma

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

sarcoplasmic reticulum membrane

nuclear membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

sarcoplasmic reticulum membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft

plasma membrane raft [inference]

caveola

Z disc

cell junction [inference]

synapse

glutamatergic synapse

T-tubule

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

neuron spine [inference]

dendritic spine

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

azurophil granule

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

primary lysosome [inference]

azurophil granule

endoplasmic reticulum [inference]

sarcoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

azurophil granule

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

postsynaptic specialization, intracellular component

postsynaptic density, intracellular component

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

primary lysosome [inference]

azurophil granule

endoplasmic reticulum [inference]

sarcoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

azurophil granule

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

postsynaptic specialization, intracellular component

postsynaptic density, intracellular component

postsynaptic specialization [inference]

postsynaptic density

neuron projection terminus

axon terminus [inference]

calyx of Held

presynapse [inference]

axon terminus [inference]

calyx of Held

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	PMID
nitric-oxide synthase activity	ISO
nitric-oxide synthase activity	TAS	12526033
nitric-oxide synthase activity	IDA	1383204 14966111 16387842 17029414 1712077 18591664 23549614 35772285
nitric-oxide synthase activity	IBA
nitric-oxide synthase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

nitric-oxide synthase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

nitric-oxide synthase activity

transferase activity [inference]

transferase activity, transferring nitrogenous groups [inference]

peptidyl-cysteine S-nitrosylase activity

catalytic activity, acting on a protein [inference]

peptidyl-cysteine S-nitrosylase activity

binding [inference]

protein binding

calmodulin binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding

enzyme binding

ATPase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

NADPH binding

ribonucleotide binding [inference]

FMN binding

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

NADPH binding

ribonucleotide binding [inference]

FMN binding

flavin adenine dinucleotide binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

FMN binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

sodium channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

nitric oxide synthase, brain

Functional Category

C: Energy production and conversion
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
FMN binding
NADP binding
calmodulin binding
flavin adenine dinucleotide binding
heme binding
metal ion binding
nitric oxide biosynthetic process
nitric-oxide synthase activity
oxidoreductase activity

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InterPro
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Flavodoxin-like
Flavodoxin/nitric oxide synthase
Flavoprotein pyridine nucleotide cytochrome reductase
Flavoprotein-like superfamily
NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
Nitric oxide synthase, N-terminal domain superfamily
Nitric oxide synthase, N-terminal
Nitric oxide synthase, domain 1 superfamily

Alliance of Genome Resources

Expression

Displaying **all 5** entries
Location	References
nuclear membrane	PMID:16387842
dendrite	PMID:12526033
azurophil granule	PMID:16387842
secretory granule	PMID:11375331
mitochondrial outer membrane	PMID:12526033

Disease

Disease Ontology

Displaying **all 9** entries
DO ID	Disease Name	Source
DOID:0080998	acute necrotizing pancreatitis	Alliance of Genome Resources
DOID:10762	portal hypertension	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources
DOID:1875	impotence	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:2316	brain ischemia	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources
DOID:783	end stage renal disease	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	4842	Xenbase:XB-GENE-487610	HUMAN15691
Drosophila melanogaster	4843	FB:FBgn0011676
Drosophila melanogaster	4846	FB:FBgn0011676
Mus musculus	18125		MOUSE45841
Drosophila melanogaster	18127	FB:FBgn0011676
Xenopus tropicalis	24598	Xenbase:XB-GENE-487610
Drosophila melanogaster	24600	FB:FBgn0011676
Danio rerio	60658		DANRE36368
Ovis aries	443533		SHEEP07373
Pan troglodytes	467139		PANTR07007

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements