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MIRAGE
platelet derived growth factor subunit B
Summary
- Gene Symbol
-
- Pdgfb
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Developmental protein
- Disulfide bond
- Glycoprotein
- Growth factor
- Mitogen
- Proto-oncogene
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A221LG85 |
|
| Q05028 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| blood vessel development | ||
| response to hypoxia | ||
| embryonic placenta development | ||
| embryonic placenta development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| cytoplasm | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| collagen binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- platelet-derived growth factor
- Functional Category
-
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Cystine-knot cytokine |
| PDGF/VEGF domain |
| Platelet-derived growth factor, conserved site |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11832 | visual epilepsy | |
| DOID:2841 | asthma | |
| DOID:2921 | glomerulonephritis | |
| DOID:3454 | brain infarction |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5154 | FB:FBgn0030964 | ||
| 5155 | Xenbase:XB-GENE-487583 | HUMAN60640 | |
| 18590 | FB:FBgn0030964 | ||
| 18591 | Xenbase:XB-GENE-487583 | MOUSE17112 | |
| 24628 | Xenbase:XB-GENE-487583 | ||
| 25266 | FB:FBgn0030964 | ||
| 442986 | CANLF01598 | ||
| 443545 | SHEEP15113 | ||
| 458844 | PANTR26617 | ||
| 540106 | BOVIN30689 |
