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MIRAGE
killer cell lectin like receptor K1
Summary
- Gene Symbol
-
- Klrk1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Adaptive immunity
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Innate immunity
- Lectin
- Receptor
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A6IM72 |
|
| A6IM69 |
|
| A6IM70 |
|
| O70215 |
|
| A0A0G2JZG3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| stimulatory C-type lectin receptor signaling pathway | ||
| stimulatory C-type lectin receptor signaling pathway | ||
| adaptive immune response | ||
| positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | ||
| nitric oxide biosynthetic process |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte migration [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| external side of plasma membrane | ||
| external side of plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| kinase binding | ||
| carbohydrate binding | ||
| MHC class Ib receptor activity | ||
| MHC class Ib receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- c-type lectin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| C-type lectin fold |
| C-type lectin-like/link domain superfamily |
| C-type lectin-like |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4231 | histiocytoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 22914 | HGNC:18788 | HUMAN11197 | |
| 24934 | HGNC:48357 | ||
| 27007 | HGNC:18788 | MOUSE49284 | |
| 396737 | PIGXX26181 | ||
| 404058 | BOVIN30264 | ||
| 450153 | PANTR05170 | ||
| 574240 | MACMU03483 | ||
| 611355 | CANLF11072 | ||
| 100053963 | HORSE37762 | ||
| 100398970 | CALJA44306 |
