ABL proto-oncogene 1, non-receptor tyrosine kinase

Summary
Gene Symbol
  • ABL1
Organism
Homo sapiens (human)
NCBI Gene
25
PubChem
25
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative splicing
  • Apoptosis
  • Autophagy
  • Cell adhesion
  • Chromosomal rearrangement
  • Cytoplasm
  • Cytoskeleton
  • DNA repair
  • DNA-binding
  • Disease variant
  • Endocytosis
  • Magnesium
  • Manganese
  • Membrane
  • Metal-binding
  • Mitochondrion
  • Myristate
  • Nucleus
  • Phosphoprotein
  • Proto-oncogene
  • Reference proteome
  • SH2 domain
  • SH3 domain
  • Tyrosine-protein kinase
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
Q59FK4
P00519
  • Abelson murine leukemia viral oncogene homolog 1
  • Abelson tyrosine-protein kinase 1
  • Proto-oncogene c-Abl
  • p150
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
Disease
Disease Ontology
Displaying all 10 entries
DO ID Disease Name Source
DOID:0050866 oral squamous cell carcinoma
DOID:0080630 B-lymphoblastic leukemia/lymphoma
DOID:10534 stomach cancer
DOID:14330 Parkinson's disease
DOID:3908 lung non-small cell carcinoma
DOID:4914 esophagus adenocarcinoma
DOID:5199 ureteral obstruction
DOID:8552 chronic myeloid leukemia
DOID:9119 acute myeloid leukemia
DOID:9256 colorectal cancer

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025