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alkaline phosphatase, placental

Summary

Gene Symbol

ALPP

Aliases

PALP
PLAP
Regan isozyme
placental alkaline phosphatase

Organism

Homo sapiens (human)

External Links

NCBI Gene

250

HGNC

439

KEGG Gene ID

hsa:250

PubChem

250

Alliance of Genome Resources

HGNC:439

Annotation

Keyword

3D-structure
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
GPI-anchor
Hydrolase
Magnesium
Metal-binding
Reference proteome
Signal
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P05187	Alkaline phosphatase Regan isozyme Placental alkaline phosphatase 1
B2R7C7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
dephosphorylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cell surface	IDA	15907827
plasma membrane	IBA IDA
side of membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

side of membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
zinc ion binding	ISS
magnesium ion binding	ISS
alkaline phosphatase activity	IBA IDA NAS	1939159 2017684 2133555 3042787
protein binding	IPI	25416956 32296183

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

alkaline phosphatase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000163283