Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fibroblast growth factor receptor 2
Summary
- Gene Symbol
-
- Fgfr2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mammary gland bud formation | ||
| positive regulation of cell population proliferation | ||
| prostate epithelial cord elongation | ||
| membranous septum morphogenesis | ||
| cellular response to fibroblast growth factor stimulus |
GO Hierarchy
- fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
- fibroblast growth factor receptor signaling pathway involved in hemopoiesis
- fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
- fibroblast growth factor receptor signaling pathway involved in mammary gland specification
- fibroblast growth factor receptor apoptotic signaling pathway
- synaptic vesicle transport
- membranous septum morphogenesis
- hair follicle morphogenesis
- lung lobe morphogenesis
- fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
- fibroblast growth factor receptor signaling pathway involved in hemopoiesis
- fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
- fibroblast growth factor receptor signaling pathway involved in mammary gland specification
- fibroblast growth factor receptor apoptotic signaling pathway
biological process
metabolic process [inference]
cellular process [inference]
signal transduction [inference]
cell surface receptor signaling pathway [inference]
enzyme-linked receptor protein signaling pathway [inference]
transmembrane receptor protein tyrosine kinase signaling pathway
fibroblast growth factor receptor signaling pathway
reproductive process [inference]
multicellular organismal process [inference]
developmental process [inference]
developmental process involved in reproduction [inference]
anatomical structure morphogenesis [inference]
morphogenesis of a branching structure [inference]
tissue morphogenesis [inference]
anatomical structure development [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
cell surface receptor signaling pathway [inference]
enzyme-linked receptor protein signaling pathway [inference]
transmembrane receptor protein tyrosine kinase signaling pathway
fibroblast growth factor receptor signaling pathway
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| cell cortex | ||
| receptor complex | ||
| collagen-containing extracellular matrix | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibroblast growth factor binding | ||
| identical protein binding | ||
| ATP binding | ||
| protein homodimerization activity | ||
| fibroblast growth factor receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- fibroblast growth factor receptor 2 isoform a
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050331 | lacrimoauriculodentodigital syndrome 1 | |
| DOID:0050660 | Beare-Stevenson cutis gyrata syndrome | |
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0080001 | bone disease | |
| DOID:0081289 | Antley-Bixler syndrome | |
| DOID:0081290 | Antley-Bixler syndrome without disordered steroidogenesis | |
| DOID:0111337 | Jackson-Weiss syndrome | |
| DOID:10283 | prostate cancer | |
| DOID:10486 | intestinal atresia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101073665 | TAKRU39460 | |||
| 101095198 | FELCA26944 | |||
| 101153046 | GORGO01094 | |||
| 101319881 | TURTR11252 | |||
| 101593125 | 10160_0:00089c | OCTDE03052 | ||
| 101594955 | 51337_0:0007c2 | JACJA10891 | ||
| 101683248 | MUSPF13860 | |||
| 101709077 | 10181_0:000871 | |||
| 101812169 | FICAL06823 | |||
| 101837200 | 10036_0:000163 |
