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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule lumen | ||
| membrane | ||
| secretory granule | ||
| perikaryon | ||
| neuronal cell body |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| endopeptidase activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5126 | HGNC:8744 | HUMAN56158 | ||
| 18549 | 10090_1:000835 | MGI:97512 | MOUSE35600 | |
| 43215 | FB:FBgn0023179 | |||
| 179412 | WB:WBGene00001172 | |||
| 281968 | BOVIN04526 | |||
| 445533 | PIGXX11301 | |||
| 458106 | PANTR24399 | |||
| 485757 | CANLF09277 | |||
| 695730 | MACMU02549 | |||
| 100004460 | ZFIN:ZDB-GENE-090608-1 | DANRE06459 |
