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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
FUS RNA binding protein
Summary
- Gene Symbol
-
- FUS
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amyotrophic lateral sclerosis
- Chromosomal rearrangement
- DNA-binding
- Direct protein sequencing
- Disease variant
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Proto-oncogene
- RNA-binding
- Reference proteome
- Repeat
- Ubl conjugation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mRNA stabilization | ||
| amyloid fibril formation | ||
| RNA splicing | ||
| positive regulation of double-strand break repair via homologous recombination | ||
| regulation of transcription by RNA polymerase II |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular non-membrane-bounded organelle | ||
| nucleoplasm | ||
| presynaptic cytosol | ||
| postsynaptic cytosol | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| DNA binding | ||
| chromatin binding | ||
| mRNA 3'-UTR binding | ||
| transcription coregulator activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- rna binding protein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060198 | amyotrophic lateral sclerosis type 6 | |
| DOID:0111431 | essential tremor 4 | |
| DOID:1115 | sarcoma | |
| DOID:1289 | neurodegenerative disease | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:3382 | liposarcoma | |
| DOID:9255 | frontotemporal dementia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 32587 | FB:FBgn0285954 | |||
| 41413 | FB:FBgn0037939 | |||
| 174175 | WB:WBGene00016173 | |||
| 233908 | MGI:1353633 | MOUSE53592 | ||
| 280796 | BOVIN20650 | |||
| 317385 | RGD:1308864 | RATNO18706 | ||
| 380075 | Xenbase:XB-GENE-495123 | |||
| 394058 | ZFIN:ZDB-GENE-040426-1010 | DANRE31472 | ||
| 100013799 | MONDO28534 | |||
| 100038234 | Xenbase:XB-GENE-495119 |
