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MIRAGE
inositol 1,4,5-trisphosphate receptor, type 1
Summary
- Gene Symbol
-
- Itpr1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Calcium channel
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Isopeptide bond
- Ligand-gated ion channel
- Metal-binding
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| single fertilization | ||
| release of sequestered calcium ion into cytosol | ||
| calcium import into the mitochondrion | ||
| positive regulation of neuron projection development | ||
| cell morphogenesis |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| presynapse | ||
| nuclear inner membrane | ||
| platelet dense granule membrane | ||
| endoplasmic reticulum | ||
| protein-containing complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| ATP binding | ||
| inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels | ||
| protein domain specific binding | ||
| transmembrane transporter binding | ||
| calcium-release channel activity |
GO Hierarchy
molecular function
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050965 | spinocerebellar ataxia type 15 | |
| DOID:0050978 | spinocerebellar ataxia type 29 | |
| DOID:0060319 | cardiac arrest | |
| DOID:0111578 | Gillespie syndrome | |
| DOID:10591 | pre-eclampsia | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11714 | gestational diabetes | |
| DOID:12858 | Huntington's disease | |
| DOID:1441 | autosomal dominant cerebellar ataxia | |
| DOID:1682 | congenital heart disease |
