Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
inositol 1,4,5-trisphosphate receptor, type 1
Summary
- Gene Symbol
-
- Itpr1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Calcium channel
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Isopeptide bond
- Ligand-gated ion channel
- Metal-binding
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| liver regeneration | ||
| cellular response to cAMP | ||
| negative regulation of calcium-mediated signaling | ||
| positive regulation of cytosolic calcium ion concentration | ||
| ligand-gated ion channel signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynapse | ||
| endoplasmic reticulum membrane | ||
| neuronal cell body | ||
| perinuclear region of cytoplasm | ||
| postsynaptic density |
| GO Term | Evidence Code | PMID |
|---|---|---|
| ATP binding | ||
| inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels | ||
| protein domain specific binding | ||
| transmembrane transporter binding | ||
| calcium-release channel activity |
GO Hierarchy
molecular function
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Inositol 1,4,5-trisphosphate receptor
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050965 | spinocerebellar ataxia type 15 | |
| DOID:0050978 | spinocerebellar ataxia type 29 | |
| DOID:0060319 | cardiac arrest | |
| DOID:0111578 | Gillespie syndrome | |
| DOID:10591 | pre-eclampsia | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11714 | gestational diabetes | |
| DOID:12858 | Huntington's disease | |
| DOID:1441 | autosomal dominant cerebellar ataxia | |
| DOID:1682 | congenital heart disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3708 | HGNC:6180 | HUMAN68200 | ||
| 16438 | 10090_1:001f35 | MGI:96623 | MOUSE49714 | |
| 40664 | FB:FBgn0010051 | |||
| 177546 | WB:WBGene00002173 | |||
| 317697 | BOVIN17442 | |||
| 397454 | PIGXX04492 | |||
| 460134 | PANTR30309 | |||
| 476548 | CANLF07320 | |||
| 567611 | ZFIN:ZDB-GENE-070604-3 | |||
| 703669 | MACMU28156 |
