GlyCosmos Portal

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q11130	Fucosyltransferase 7 Fucosyltransferase VII Galactoside 3-L-fucosyltransferase Selectin ligand synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
embryo implantation	IMP	18402946
regulation of insulin receptor signaling pathway	IMP	17229154
positive regulation of leukocyte adhesion to vascular endothelial cell	IMP	29138114
ceramide metabolic process	IDA	9299472
positive regulation of cell adhesion	IMP	10386892

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte migration involved in immune response

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

T cell activation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

glycosylation [inference]

fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

T cell activation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

reproductive process [inference]

embryo implantation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

T cell activation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

regulation of immune effector process [inference]

regulation of leukocyte mediated immunity [inference]

regulation of lymphocyte mediated immunity [inference]

regulation of T cell mediated immunity [inference]

regulation of type IV hypersensitivity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of insulin receptor signaling pathway

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cellular process [inference]

positive regulation of cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of insulin receptor signaling pathway

regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of insulin receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell adhesion molecule production

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	HDA	19946888
Golgi apparatus	IDA TAS	11698403
Golgi cisterna membrane	IEA
trans-Golgi network	IDA	23192350
Golgi membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
alpha-(1->3)-fucosyltransferase activity	IBA IDA IMP TAS	11278338 11698403 15926890 23192350 8207002 9299472 9405391 9461592
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IDA	9473504
fucosyltransferase activity	IDA	11404359 9299472

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity

alpha-(1->3)-fucosyltransferase activity

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Fucosyltransferase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
alpha-(1->3)-fucosyltransferase activity
fucosylation
fucosyltransferase activity
transferase activity

Displaying **all 3** entries
InterPro
Fucosyltransferase, N-terminal
GT10-like, C-terminal domain superfamily
Glycosyl transferase family 10

GlycoGene Database (GGDB)

GGDB ID

gg007

Gene Symbol

FUT7

Reactions

Displaying **all 3** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
GDP-Fuc	G22418PV	R	G19619KS	R	9461592
GDP-Fuc	G00065MO	R	G00054MO	R	8207002
GDP-Fuc	G31119YY	R	G51911JA	R	10622713

Displaying **all 3** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
GDP-Fuc	G22418PV	R	G19619KS	R	9461592
GDP-Fuc	G00065MO	R	G00054MO	R	8207002
GDP-Fuc	G31119YY	R	G51911JA	R	10622713 9461592

Displaying entry **6 - 6** of 6 in total

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Donor	Acceptor	Reducing terminal(Acceptor)	Reference
GDP-Fuc	G78941GA	Free	8182079

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	NP_955785	NM_199491
Mus musculus	NP_038552	NM_013524

KEGG BRITE Database

Orthology

K07635

Name

galactoside alpha-1,3-fucosyltransferase 7 [EC:2.4.1.-]

References

8207002

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06075	2.4.1.- 2.4.1.65	G01767JJ	G96401FK

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1508	candidiasis	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000249
Gene Name: fucosyltransferase 7 (alpha (1,3) fucosyltransferase)

Ortholog

Displaying entries **11 - 20** of 72 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Monodelphis domestica	100022510		MONDO06301
Bos taurus	100036592		BOVIN03517
Equus caballus	100067846		HORSE24010
Pongo abelii	100462257	9601_0:0027ec	PONAB35520
Nomascus leucogenys	100593653		NOMLE35699
Oreochromis niloticus	100690516		ORENI11776
Cavia porcellus	100717385		CAVPO09666
Cricetulus griseus	100772214		CRIGR25706
Pan paniscus	100984904	9597_0:0029d5	PANPA40710
Papio anubis	101012920		PAPAN08936

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements