GlyCosmos Portal

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Ion transport
Reference proteome
Signal-anchor
Sodium/potassium transport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q63377	Sodium/potassium-dependent ATPase subunit beta-3
A6I275

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

1

2

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GO Term	Evidence Code	PMID
protein stabilization	ISO
metal ion transport	IDA	15327400
sodium ion transport	IDA IEA	16624992
potassium ion import across plasma membrane	IBA ISO
intracellular sodium ion homeostasis	IBA ISO

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

sodium ion transport

sodium ion transmembrane transport

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

regulation of potassium ion transport [inference]

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of transport [inference]

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

regulation of membrane potential [inference]

membrane repolarization

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

regulation of potassium ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

regulation of ATP-dependent activity [inference]

positive regulation of ATP-dependent activity

positive regulation of molecular function [inference]

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of ATP-dependent activity

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
sodium:potassium-exchanging ATPase complex	IBA IDA IEA ISO	16624992
apical plasma membrane	IDA IEA	9950762
plasma membrane	ISO
melanosome	IEA
basolateral plasma membrane	IDA IEA	9950762

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

sodium:potassium-exchanging ATPase complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	9950762
P-type sodium:potassium-exchanging transporter activity	IC IDA TAS	12562669 15327400 16624992
protein-macromolecule adaptor activity	ISO
ATPase activator activity	IBA ISO
ATPase binding	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

binding [inference]

protein binding

enzyme binding [inference]

ATPase binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

molecular function regulator activity [inference]

ATPase regulator activity [inference]

ATPase activator activity

molecular function activator activity [inference]

ATPase activator activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

sodium/potassium-transporting ATPase subunit beta-3

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATPase activator activity
intracellular sodium ion homeostasis
monoatomic ion transport

Displaying **all 2** entries
InterPro
Sodium/potassium-transporting ATPase subunit beta superfamily
Sodium/potassium-transporting ATPase subunit beta

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
caveola	PMID:16624992
sodium	PMID:16624992

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1826	epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **131 - 134** of **134** in total

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Species	Gene ID	OrthoDB
Peromyscus californicus insignis	128109409	564181_0:000e60
Psammomys obesus	129693172	48139_1:004128
Chionomys nivalis	130872947	269649_0:001545
Peromyscus eremicus	131915286	42410_0:002731

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements