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cathepsin E

Summary

Gene Symbol

Ctse

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25424

PubChem

25424

Alliance of Genome Resources

RGD:2446

Annotation

Keyword

Alternative splicing
Aspartyl protease
Autocatalytic cleavage
Direct protein sequencing
Disulfide bond
Endosome
Glycoprotein
Reference proteome
Signal
Zymogen

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6IC25
P16228

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
proteolysis	ISO
proteolysis	IBA
protein autoprocessing	IMP	16367762
antigen processing and presentation of exogenous peptide antigen via MHC class II	ISO
antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	8491674

GO Hierarchy

biological process

immune system process [inference]

antigen processing and presentation [inference]

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [inference]

antigen processing and presentation of peptide antigen via MHC class II [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class II

antigen processing and presentation of exogenous antigen [inference]

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class II

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class II

antigen processing and presentation of peptide antigen via MHC class II [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class II

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein maturation [inference]

protein processing [inference]

protein autoprocessing

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endosome	ISO
endosome	IDA	9572291
endosome	IBA
intracellular membrane-bounded organelle	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
aspartic-type endopeptidase activity	ISO
aspartic-type endopeptidase activity	IDA	8157122
aspartic-type endopeptidase activity	IBA
peptidase activity	ISO
identical protein binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity [inference]

aspartic-type endopeptidase activity

aspartic-type peptidase activity [inference]

aspartic-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity [inference]

aspartic-type endopeptidase activity

aspartic-type peptidase activity [inference]

aspartic-type endopeptidase activity

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protease

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
aspartic-type endopeptidase activity
hydrolase activity
proteolysis

Displaying **all 4** entries
InterPro
Aspartic peptidase A1 family
Aspartic peptidase domain superfamily
Aspartic peptidase, active site
Peptidase family A1 domain

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	1509	SGD:S000006075
Homo sapiens	1510	Xenbase:XB-GENE-947864	HUMAN54426
Saccharomyces cerevisiae S288C	5972	SGD:S000006075
Saccharomyces cerevisiae S288C	9476	SGD:S000006075
Saccharomyces cerevisiae S288C	13033	SGD:S000006075
Mus musculus	13034	Xenbase:XB-GENE-947864	MOUSE28675
Saccharomyces cerevisiae S288C	16541	SGD:S000006075
Saccharomyces cerevisiae S288C	19701	SGD:S000006075
Saccharomyces cerevisiae S288C	24715	SGD:S000006075
Xenopus tropicalis	25424	Xenbase:XB-GENE-947864