GlyCosmos Portal

Displaying entries **1 - 5** of 51 in total

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GO Term	Evidence Code	PMID
G-protein alpha-subunit binding	IPI	19764351
protein tyrosine kinase activity	ISS
protein tyrosine kinase activity	ISO
protein tyrosine kinase activity	IDA	16909201
GPI-linked ephrin receptor activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

structural molecule activity

transporter activity [inference]

protein transporter activity

binding [inference]

protein binding

G-protein alpha-subunit binding

signaling receptor binding [inference]

insulin receptor binding

growth factor binding [inference]

insulin-like growth factor binding

insulin-like growth factor I binding

amide binding [inference]

peptide binding [inference]

peptide hormone binding [inference]

insulin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

hormone binding [inference]

peptide hormone binding [inference]

insulin binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

ephrin receptor activity [inference]

platelet-derived growth factor receptor activity [inference]

collagen receptor activity [inference]

protein tyrosine kinase collagen receptor activity

neurotrophin receptor activity [inference]

brain-derived neurotrophic factor receptor activity

protein-hormone receptor activity [inference]

insulin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

insulin-like growth factor 1 receptor

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

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Gene Ontology
ATP binding
cellular response to glucose stimulus
insulin receptor activity
insulin receptor substrate binding
insulin-like growth factor receptor signaling pathway
kinase activity
nucleotide binding
phosphatidylinositol 3-kinase binding
phosphorylation
positive regulation of MAPK cascade

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InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Receptor L-domain superfamily
Receptor L-domain
Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyrosine-protein kinase, catalytic domain

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
caveola	PMID:18022157
axon	PMID:23349896
neuronal cell body	PMID:19862643
T-tubule	PMID:23118311

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources
DOID:2526	prostate adenocarcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3480	Xenbase:XB-GENE-484032	HUMAN25193
Drosophila melanogaster	3643	FB:FBgn0283499
Drosophila melanogaster	3645	FB:FBgn0283499
Mus musculus	16001	Xenbase:XB-GENE-484032	MOUSE52615
Drosophila melanogaster	16337	FB:FBgn0283499
Drosophila melanogaster	23920	FB:FBgn0283499
Xenopus tropicalis	25718	Xenbase:XB-GENE-484032
Xenopus tropicalis	42549	Xenbase:XB-GENE-484032
Drosophila melanogaster	60663	FB:FBgn0283499
Xenopus tropicalis	175410	Xenbase:XB-GENE-484032

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements