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SAMM50 sorting and assembly machinery component

Summary

Gene Symbol

SAMM50

Organism

Homo sapiens (human)

External Links

NCBI Gene

25813

PubChem

25813

Alliance of Genome Resources

HGNC:24276

Annotation

Keyword

3D-structure
Cytoplasm
Methylation
Mitochondrion outer membrane
Reference proteome
Transmembrane beta strand

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y512	Transformation-related gene 3 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein insertion into mitochondrial outer membrane	IBA IDA NAS	15644312 31387448
cristae formation	IMP	22252321 25781180
inner mitochondrial membrane organization	IC	26477565
mitochondrial respiratory chain complex assembly	IBA IMP	22252321

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial membrane organization [inference]

inner mitochondrial membrane organization

cristae formation

outer mitochondrial membrane organization [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

cellular component assembly [inference]

protein-containing complex assembly [inference]

mitochondrial respiratory chain complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

mitochondrial respiratory chain complex assembly

membrane organization [inference]

mitochondrial membrane organization [inference]

inner mitochondrial membrane organization

cristae formation

outer mitochondrial membrane organization [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of localization [inference]

transport [inference]

mitochondrial transport [inference]

protein insertion into mitochondrial outer membrane

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial outer membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	IDA	15644312
mitochondrial outer membrane	IDA NAS	15644312 31387448
mitochondrion	HDA HTP IDA	15644312 20833797 25781180 34800366
MIB complex	HDA	26477565
SAM complex	HDA IMP IPI	15644312 17510655 26477565

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

outer mitochondrial membrane protein complex [inference]

mitochondrial outer membrane translocase complex [inference]

SAM complex

inner mitochondrial membrane protein complex [inference]

MIB complex

mitochondrial protein-containing complex [inference]

outer mitochondrial membrane protein complex [inference]

mitochondrial outer membrane translocase complex [inference]

SAM complex

inner mitochondrial membrane protein complex [inference]

MIB complex

cellular anatomical entity [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

mitochondrion

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	21081504 25416956 27059175 31644573 32296183 33961781

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

assembly machinery

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
mitochondrial respiratory chain complex assembly
protein insertion into mitochondrial outer membrane

Displaying **all 2** entries
InterPro
Bacterial surface antigen (D15)
Surface antigen D15-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 86 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	36675		FB:FBgn0033989
Mus musculus	68653		MGI:1915903	MOUSE15337
Caenorhabditis elegans	175723		WB:WBGene00001662
Rattus norvegicus	300111		RGD:1303219	RATNO38242
Xenopus laevis	379807		Xenbase:XB-GENE-6254691
Danio rerio	393111		ZFIN:ZDB-GENE-040426-806	DANRE27758
Xenopus tropicalis	394743		Xenbase:XB-GENE-6456163
Xenopus laevis	398869		Xenbase:XB-GENE-6255146
Pan troglodytes	470281	9598_0:005392		PANTR26782
Danio rerio	492471		ZFIN:ZDB-GENE-041114-30