GlyCosmos Portal

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
ligand-gated monoatomic ion channel activity	IDA	27071117
ATP binding	IDA IEA	12127972 22535247 24082111 24878662 25175421 27071117 28332633 33901491
purine nucleotide binding	IDA	25597706
ATP-gated ion channel activity	IDA	31024257
nucleotide binding	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

extracellularly ATP-gated monoatomic cation channel activity

ATP-gated ion channel activity

extracellularly ATP-gated monoatomic cation channel activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

purine nucleotide binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine nucleotide binding [inference]

pyrimidine ribonucleotide binding [inference]

CTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine ribonucleotide binding [inference]

CTP binding

ion binding [inference]

anion binding [inference]

CTP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

purine nucleotide binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine nucleotide binding [inference]

pyrimidine ribonucleotide binding [inference]

CTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine ribonucleotide binding [inference]

CTP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

pyrimidine ribonucleotide binding [inference]

CTP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

nucleotide receptor activity [inference]

purinergic nucleotide receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

p2X purinoceptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
calcium ion transmembrane transport
excitatory postsynaptic potential
extracellularly ATP-gated monoatomic cation channel activity
monoatomic ion channel activity
monoatomic ion transport
response to ATP

Displaying **all 2** entries
InterPro
P2X purinoreceptor extracellular domain superfamily
P2X purinoreceptor

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:6000	congestive heart failure	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **257** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5025	HGNC:8535	HUMAN15907
Mus musculus	18438	MGI:1338859	MOUSE43460
Rattus norvegicus	29659	RGD:62073	RATNO05042
Bos taurus	338036		BOVIN09473
Canis lupus familiaris	448783		CANLF10290
Sus scrofa	497623		PIGXX06798
Macaca mulatta	702536		MACMU03941
Oryctolagus cuniculus	100008720		RABIT09132
Equus caballus	100059626		HORSE40814
Sus scrofa	100157723		PIGXX06798