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zinc finger ZZ-type containing 3

Summary

Gene Symbol

ZZZ3

Organism

Homo sapiens (human)

External Links

NCBI Gene

26009

PubChem

26009

Alliance of Genome Resources

HGNC:24523

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
DNA-binding
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IYH5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
chromatin organization	IMP	30217978
regulation of DNA-templated transcription	ISS
regulation of transcription, DNA-templated	ISS
regulation of DNA-templated transcription	IMP	19936620
regulation of transcription, DNA-templated	IMP	19936620

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein deacetylation [inference]

regulation of tubulin deacetylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein deacetylation [inference]

regulation of tubulin deacetylation

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein deacetylation [inference]

regulation of tubulin deacetylation

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
nucleoplasm	IDA
nucleolus	IDA
mitotic spindle	NAS	20562830
ATAC complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

protein acetyltransferase complex [inference]

histone acetyltransferase complex [inference]

SAGA-type complex [inference]

ATAC complex

catalytic complex [inference]

transferase complex [inference]

acetyltransferase complex [inference]

protein acetyltransferase complex [inference]

histone acetyltransferase complex [inference]

SAGA-type complex [inference]

ATAC complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
DNA binding	IEA
protein binding	IPI	20562830 23088713 24981860 25416956 27705803 32296183 33961781
zinc ion binding	IEA
methylated histone binding	IDA	30217978
lysine-acetylated histone binding	IDA	30217978

GO Hierarchy

molecular function

binding [inference]

protein binding

histone binding [inference]

modification-dependent protein binding [inference]

acetylation-dependent protein binding [inference]

lysine-acetylated histone binding

methylation-dependent protein binding [inference]

methylated histone binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

chromatin-protein adaptor activity [inference]

histone reader activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ZZ-type zinc finger-containing protein 3

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
metal ion binding
zinc ion binding

Displaying 1 entry
InterPro
ZZ-type zinc finger-containing protein 3

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	26009	Xenbase:XB-GENE-993548
Mus musculus	108946	Xenbase:XB-GENE-993548	MOUSE36826
Rattus norvegicus	310958		RATNO22791
Pan troglodytes	456964		PANTR21428
Canis lupus familiaris	490203		CANLF16980
Bos taurus	538498		BOVIN26686
Danio rerio	567022		DANRE28474
Macaca mulatta	706357		MACMU25062
Equus caballus	100053222		HORSE34785
Ornithorhynchus anatinus	100074855		ORNAN19664