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adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

Summary

Gene Symbol

APPL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

26060

PubChem

26060

Alliance of Genome Resources

HGNC:24035

Annotation

Keyword

3D-structure
Cell cycle
Cell projection
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Diabetes mellitus
Disease variant
Endosome
Membrane
Nucleus
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UKG1	Adapter protein containing PH domain, PTB domain and leucine zipper motif 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
regulation of innate immune response	ISS
regulation of protein localization to plasma membrane	IMP	17848569
transforming growth factor beta receptor signaling pathway	IMP	26583432
regulation of fibroblast migration	ISS
protein import into nucleus	IDA	26583432

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cytokine-mediated signaling pathway [inference]

adiponectin-activated signaling pathway

hormone-mediated signaling pathway [inference]

adiponectin-activated signaling pathway

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

cell junction maintenance [inference]

maintenance of synapse structure

synapse organization [inference]

maintenance of synapse structure

cellular component maintenance [inference]

cell junction maintenance [inference]

maintenance of synapse structure

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

response to hepatocyte growth factor [inference]

cellular response to hepatocyte growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to hepatocyte growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to hepatocyte growth factor stimulus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of immune response [inference]

regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of secondary metabolic process [inference]

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

signaling

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of glucose import

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of pinocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of macropinocytosis [inference]

positive regulation of macropinocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of response to external stimulus [inference]

regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of immune response [inference]

regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cytokine-mediated signaling pathway [inference]

adiponectin-activated signaling pathway

hormone-mediated signaling pathway [inference]

adiponectin-activated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of glucose import

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of melanin biosynthetic process

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of pinocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of macropinocytosis [inference]

positive regulation of macropinocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

regulation of G1/S transition of mitotic cell cycle

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of endocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of pinocytosis [inference]

positive regulation of pinocytosis [inference]

positive regulation of macropinocytosis

regulation of macropinocytosis [inference]

positive regulation of macropinocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis [inference]

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in inflammatory response

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
vesicle membrane	IDA	17848569
cytoplasmic vesicle	IDA	18034774
membrane	IDA	18034774
early endosome	IDA ISS	21645192
postsynapse	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane

cytoplasmic vesicle membrane [inference]

endosome membrane

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane

early endosome membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

ruffle

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle

cytoplasmic vesicle

endosome

early endosome

pinosome [inference]

macropinosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle

cytoplasmic vesicle

endosome

early endosome

pinosome [inference]

macropinosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle

cytoplasmic vesicle

endosome

early endosome

pinosome [inference]

macropinosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10490823 12011067 15016378 16189514 16273093 16622416 17030088 17581628 18034774 19433865 19661063 21233288 21291857 21645192 23414517 23752268 24879834 25241761 25416956 25814554 26583432 28514442 29568061 31515488 32296183 33961781 35271311 35384245
protein-containing complex binding	IPI	15016378
phosphatidylinositol binding	IDA	18034774
identical protein binding	IPI	17502098 17581628 18034774 25416956 31515488 32296183 35271311
beta-tubulin binding	IDA	26583432

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

beta-tubulin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase B binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

lipid binding [inference]

phospholipid binding [inference]

protein-containing complex binding

modified amino acid binding [inference]

phosphatidylserine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
AH/BAR domain superfamily
BAR domain
PH-like domain superfamily
Pleckstrin homology domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111111	maturity-onset diabetes of the young type 14	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 83 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	100038055		Xenbase:XB-GENE-855791
Equus caballus	100058653			HORSE11493
Ornithorhynchus anatinus	100089140			ORNAN28988
Sus scrofa	100188978			PIGXX04318
Taeniopygia guttata	100226921			TAEGU03859
Oryctolagus cuniculus	100353097			RABIT12944
Callithrix jacchus	100389847			CALJA11682
Macaca mulatta	100425753			MACMU28879
Pongo abelii	100442490	9601_0:001299		PONAB25609
Ailuropoda melanoleuca	100463883			AILME18534

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements