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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
GDNF family receptor alpha 2
Summary
- Gene Symbol
-
- GFRA2
- Aliases
-
- GDNFRB
- NTNRA
- RETL2
- TRNR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- GPI-anchor
- Receptor
- Reference proteome
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| O00451 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| glial cell-derived neurotrophic factor receptor signaling pathway | ||
| nervous system development | ||
| transmembrane receptor protein tyrosine kinase signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| receptor complex | ||
| plasma membrane | ||
| extrinsic component of membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| glial cell-derived neurotrophic factor receptor activity | ||
| heparan sulfate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- GDNF receptor alpha
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| glial cell-derived neurotrophic factor receptor activity |
| nervous system development |
| InterPro |
|---|
| GDNF receptor alpha |
| GDNF/GAS1 |
| Glial cell line-derived neurotrophic factor receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080855 | Parkinsonism |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101875344 | MELUD19721 | |||
| 101932742 | CHRPI07497 | |||
| 101970657 | ICTTR02046 | |||
| 102027601 | CHILA00698 | |||
| 102136800 | MACFA40430 | |||
| 102166950 | PIGXX06350 | |||
| 102178626 | CAPHI29249 | |||
| 102427692 | MYOLU14412 | |||
| 103215429 | CHLSB16948 | |||
| 103673328 | URSMA23990 |
