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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth hormone secretagogue receptor
Summary
- Gene Symbol
-
- GHSR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Dwarfism
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q92847 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of hindgut contraction | ||
| negative regulation of tumor necrosis factor production | ||
| response to L-glutamate | ||
| positive regulation of small intestine smooth muscle contraction | ||
| regulation of gastric motility |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
negative regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Schaffer collateral - CA1 synapse | ||
| postsynapse | ||
| plasma membrane | ||
| membrane raft | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| growth hormone secretagogue receptor activity | ||
| peptide hormone binding | ||
| identical protein binding | ||
| G protein-coupled receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- G_PROTEIN_RECEP_F1_2 domain-containing protein
- Functional Category
-
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050848 | obstructive sleep apnea | |
| DOID:0060870 | isolated growth hormone deficiency | |
| DOID:1824 | status epilepticus | |
| DOID:224 | transient cerebral ischemia | |
| DOID:3125 | multiple endocrine neoplasia | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 84022 | RGD:621397 | RATNO22904 | ||
| 208188 | MGI:2441906 | MOUSE38715 | ||
| 397372 | PIGXX05136 | |||
| 443238 | SHEEP01620 | |||
| 460851 | 9598_0:001219 | PANTR32654 | ||
| 514203 | BOVIN14994 | |||
| 694587 | MACMU28395 | |||
| 795753 | ZFIN:ZDB-GENE-070912-238 | DANRE29563 | ||
| 100010258 | MONDO31630 | |||
| 100057865 | HORSE14857 |
