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Guidelines

MIRAGE

NLR family member X1

Summary

Gene Symbol

Nlrx1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

270151

PubChem

270151

Alliance of Genome Resources

MGI:2429611

Annotation

Keyword

ATP-binding
Host-virus interaction
Innate immunity
Leucine-rich repeat
Mitochondrion outer membrane
Reference proteome
Repeat
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3TL44

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
macrophage cytokine production	IMP	21703540
negative regulation of macrophage cytokine production	IMP	21703540
interferon-beta production	IMP	21703540
interleukin-6 production	IMP	21703540
negative regulation of interferon-beta production	IMP	21703540

GO Hierarchy

biological process

immune system process [inference]

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

immune response [inference]

innate immune response

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

multicellular organismal process [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

myeloid leukocyte cytokine production [inference]

macrophage cytokine production

type I interferon production [inference]

interferon-beta production

interleukin-6 production

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IBA
mitochondrion	HDA	18614015
mitochondrial outer membrane	IEA
plasma membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21703540
ATP binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: April 6, 2026