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Guidelines

MIRAGE

lysosomal associated membrane protein 3

Summary

Gene Symbol

LAMP3

Organism

Homo sapiens (human)

External Links

NCBI Gene

27074

PubChem

27074

Alliance of Genome Resources

HGNC:14582

JoGo

LAMP3

TogoVar

LAMP3

Annotation

Keyword

3D-structure
Adaptive immunity
Cytoplasmic vesicle
Disulfide bond
Endosome
Glycoprotein
Host-virus interaction
Lysosome
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UQV4	DC-lysosome-associated membrane glycoprotein Protein TSC403

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

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GO Term	Evidence Code	PMID
adaptive immune response	IEA
regulation of autophagy	IMP	25681212
positive regulation of gene expression	IMP	23651994
response to interferon-alpha	IMP	23651994
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle

establishment of protein localization [inference]

establishment of protein localization to organelle

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

immune response [inference]

adaptive immune response

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to interferon-alpha

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle

establishment of protein localization [inference]

establishment of protein localization to organelle

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to organelle

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle

establishment of protein localization [inference]

establishment of protein localization to organelle

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of cellular catabolic process [inference]

regulation of autophagy

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular catabolic process [inference]

regulation of autophagy

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of proteolysis involved in protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of viral process [inference]

regulation of viral life cycle

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular catabolic process [inference]

regulation of autophagy

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
lysosomal membrane	IBA
early endosome	IDA	21810281
plasma membrane	IDA	21810281
plasma membrane	IBA
cell surface	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

secretory granule membrane [inference]

lamellar body membrane [inference]

alveolar lamellar body membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

secretory granule membrane [inference]

lamellar body membrane [inference]

alveolar lamellar body membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

perinuclear region of cytoplasm

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: April 6, 2026