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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
forkhead box P1
Summary
- Gene Symbol
-
- FOXP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Chromosomal rearrangement
- DNA-binding
- Disease variant
- Intellectual disability
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A3B3IT66 |
|
| Q8N2P0 |
|
| Q548T7 |
|
| Q9H334 |
|
| Q8TEA2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of chemokine (C-X-C motif) ligand 2 production | ||
| negative regulation of cell growth involved in cardiac muscle cell development | ||
| regulation of tumor necrosis factor production | ||
| regulation of interleukin-1 beta production | ||
| striatum development |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| metal ion binding | ||
| identical protein binding | ||
| sequence-specific double-stranded DNA binding |
GO Hierarchy
molecular function
binding [inference]
organic cyclic compound binding [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Forkhead box protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| sequence-specific DNA binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060038 | specific developmental disorder | |
| DOID:0090131 | complex cortical dysplasia with other brain malformations | |
| DOID:0111331 | intellectual disability-severe speech delay-mild dysmorphism syndrome | |
| DOID:1255 | trichostrongyloidiasis | |
| DOID:12858 | Huntington's disease | |
| DOID:1682 | congenital heart disease | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:4914 | esophagus adenocarcinoma | |
| DOID:5419 | schizophrenia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 41182 | FB:FBgn0262477 | |||
| 108655 | MGI:1914004 | MOUSE49257 | ||
| 177340 | WB:WBGene00001439 | |||
| 297480 | RGD:1308669 | RATNO31878 | ||
| 484692 | CANLF07344 | |||
| 496386 | Xenbase:XB-GENE-961750 | |||
| 564127 | ZFIN:ZDB-GENE-060929-624 | |||
| 569047 | ZFIN:ZDB-GENE-041203-1 | DANRE38790 | ||
| 694726 | MACMU30319 | |||
| 736525 | 9598_0:00105d | PANTR31554 |
