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syndecan binding protein 2

Summary

Gene Symbol

SDCBP2

Aliases

SITAC18
ST-2
syntenin-2

Organism

Homo sapiens (human)

External Links

NCBI Gene

27111

HGNC

15756

KEGG Gene ID

hsa:27111

PubChem

27111

Alliance of Genome Resources

HGNC:15756

Annotation

Keyword

Alternative splicing
Cell membrane
Cytoplasm
Lipid-binding
Nucleus
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9H190	Similar to TACIP18 Syndecan-binding protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nervous system development		11152476
intracellular transport		11152476
cell population proliferation	IMP	15961997
intracellular signal transduction		11152476

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction

cell population proliferation

cellular localization [inference]

intracellular transport

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport

establishment of localization in cell [inference]

intracellular transport

cellular localization [inference]

intracellular transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytosol	IDA
cytoplasm	IBA IDA	11152476 15961997
nuclear speck	IDA	15961997
plasma membrane	IBA IC IDA	11152476 15961997
Golgi apparatus	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

nucleolus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein homodimerization activity	IDA	11152476
phosphatidylinositol-4,5-bisphosphate binding	IDA	15961997
protein binding	IPI	11102519 11152476 16189514 21516116 25416956 27107012 31515488 32296183
protein heterodimerization activity	IPI	11152476
identical protein binding	IPI	25416956 27107012

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000125775

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K17254

Name

syntenin-1

References

Disease

Disease Ontology

Displaying entries **1 - 10** of 23 in total

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DO ID	Disease Name	Source
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:0080348	Alzheimer's disease 1	DisGeNET
DOID:0110035	Alzheimer's disease 2	DisGeNET
DOID:0110037	Alzheimer's disease 5	DisGeNET
DOID:0110038	Alzheimer's disease 6	DisGeNET
DOID:0110039	Alzheimer's disease 7	DisGeNET
DOID:0110041	Alzheimer's disease 8	DisGeNET
DOID:0110043	Alzheimer's disease 10	DisGeNET
DOID:0110044	Alzheimer's disease 11	DisGeNET
DOID:0110045	Alzheimer's disease 12	DisGeNET

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	41592	FB:FBgn0051342
Latimeria chalumnae	102364640		LATCH08449
Danio rerio	325004	ZFIN:ZDB-GENE-030131-3727
Crocodylus porosus	109313056		CROPO22374
Meleagris gallopavo	100541577		MELGA07340
Serinus canaria	103818684		SERCA13426
Sarcophilus harrisii	100917214		SARHA05615
Erinaceus europaeus	103113480		ERIEU07750
Callithrix jacchus	100398458		CALJA34767
Cercocebus atys	105582187		CERAT03274

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024