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MORC family CW-type zinc finger 1

Summary

Gene Symbol

MORC1

Organism

Homo sapiens (human)

External Links

NCBI Gene

27136

PubChem

27136

Alliance of Genome Resources

HGNC:7198

Annotation

Keyword

Alternative splicing
Coiled coil
Developmental protein
Nucleus
Proteomics identification
RNA-mediated gene silencing
Reference proteome
Spermatogenesis
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86VD1	Cancer/testis antigen 33

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
behavioral fear response	IEA
epigenetic programing of male pronucleus	IEA
spermatogenesis	IEA
gene silencing by RNA	IEA
retrotransposon silencing by heterochromatin formation	IEA

GO Hierarchy

biological process

cellular process [inference]

transposition [inference]

retrotransposition

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of male pronucleus

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

multicellular organismal process [inference]

behavior [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

cellular developmental process [inference]

cell differentiation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of male pronucleus

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of male pronucleus

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of male pronucleus

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular process [inference]

retrotransposon silencing [inference]

retrotransposon silencing by heterochromatin formation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of male pronucleus

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

regulation of DNA-templated transcription initiation [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of cellular process [inference]

retrotransposon silencing [inference]

retrotransposon silencing by heterochromatin formation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription initiation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
male germ cell nucleus	IEA
nucleus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28514442 33961781
zinc ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dyneins heavy chain

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Kelch-type beta propeller

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1595	melancholic depression	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 30 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	17450		MGI:1316740	MOUSE17887
Caenorhabditis elegans	175711		WB:WBGene00022531
Rattus norvegicus	360712		RGD:1565610	RATNO04731
Pan troglodytes	470878	9598_0:0010bb		PANTR31793
Monodelphis domestica	100010638			MONDO21148
Equus caballus	100071799			HORSE14546
Callithrix jacchus	100399625			CALJA12026
Pongo abelii	100443225	9601_0:001096		PONAB26102
Nomascus leucogenys	100605195			NOMLE19553
Cricetulus griseus	100759800			CRIGR06927

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements