argonaute RISC catalytic component 2

Summary
Gene Symbol
  • AGO2
Organism
Homo sapiens (human)
NCBI Gene
27161
PubChem
27161
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Endonuclease
  • Host-virus interaction
  • Hydroxylation
  • Intellectual disability
  • Magnesium
  • Manganese
  • Metal-binding
  • Nitration
  • Nucleus
  • Phosphoprotein
  • RNA-binding
  • RNA-mediated gene silencing
  • Reference proteome
  • Repressor
  • Ribonucleoprotein
  • Transcription regulation
  • Translation regulation
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q9UKV8
  • Argonaute RISC catalytic component 2
  • Eukaryotic translation initiation factor 2C 2
  • PAZ Piwi domain protein
  • Protein slicer
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
argonaute
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0060001 withdrawal disorder
DOID:1686 glaucoma
DOID:2560 morphine dependence

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024