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sialic acid binding Ig like lectin 8

Summary

Gene Symbol

SIGLEC8

Aliases

MGC59785
SAF2
SIGLEC-8
SIGLEC8L

Organism

Homo sapiens (human)

External Links

NCBI Gene

27181

HGNC

10877

KEGG Gene ID

hsa:27181

PubChem

27181

Alliance of Genome Resources

HGNC:10877

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Disulfide bond
Glycoprotein
Immunoglobulin domain
Lectin
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NYZ4	Sialoadhesin family member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cell adhesion	IBA
signal transduction	TAS	10625619

GO Hierarchy

biological process

cellular process [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	TAS	10625619
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21982860
sialic acid binding	IBA
carbohydrate binding	IEA
transmembrane signaling receptor activity	TAS	10625619

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

sialic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

sialic acid binding

carbohydrate derivative binding [inference]

sialic acid binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Immunoglobulin

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
InterPro
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Human Protein Atlas

ENSG00000105366

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)