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vacuolar protein sorting 4 homolog A

Summary

Gene Symbol

VPS4A

Aliases

FLJ22197
SKD1
SKD1A
SKD2
VPS4
VPS4-1

Organism

Homo sapiens (human)

External Links

NCBI Gene

27183

HGNC

13488

PubChem

27183

Alliance of Genome Resources

HGNC:13488

JoGo

VPS4A

TogoVar

VPS4A

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Cataract
Cell division
Congenital dyserythropoietic anemia
Cytoskeleton
Disease variant
Endosome
Hydrolase
Intellectual disability
Membrane
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UN37	Protein SKD2 VPS4-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 44 in total

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GO Term	Evidence Code	PMID
actomyosin contractile ring contraction	TAS	28242692
plasma membrane repair	NAS	24482116
protein targeting to lysosome	IMP	16973552
vesicle budding from membrane	IMP	15075231
autophagy	NAS	17428789

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

catabolic process [inference]

cellular catabolic process [inference]

autophagy

macroautophagy

microautophagy [inference]

late endosomal microautophagy

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

macroautophagy

microautophagy [inference]

late endosomal microautophagy

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

vesicle-mediated transport

endosome to lysosome transport [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

multivesicular body sorting pathway

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis

cytokinetic process [inference]

contractile ring contraction [inference]

actomyosin contractile ring contraction

mitotic cytokinetic process [inference]

midbody abscission

mitotic cell cycle process [inference]

mitotic metaphase chromosome alignment

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

mitotic nuclear membrane organization [inference]

mitotic nuclear membrane reassembly

mitotic cytokinetic process [inference]

midbody abscission

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

macroautophagy

microautophagy [inference]

late endosomal microautophagy

cell division

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to lysosome transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

process utilizing autophagic mechanism [inference]

autophagy

macroautophagy

microautophagy [inference]

late endosomal microautophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane

vesicle fusion [inference]

endosomal vesicle fusion

endosome organization [inference]

multivesicular body organization [inference]

multivesicular body assembly

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

organelle assembly [inference]

multivesicular body assembly

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

protein depolymerization [inference]

vesicle uncoating

autophagosome maturation

ESCRT complex disassembly

ESCRT III complex disassembly

cellular component assembly [inference]

organelle assembly [inference]

multivesicular body assembly

membrane assembly [inference]

nuclear membrane reassembly

mitotic nuclear membrane reassembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

protein depolymerization [inference]

vesicle uncoating

autophagosome maturation

ESCRT complex disassembly

ESCRT III complex disassembly

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane repair

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

midbody abscission

membrane assembly [inference]

nuclear membrane reassembly

mitotic nuclear membrane reassembly

nuclear membrane organization [inference]

nuclear membrane reassembly

mitotic nuclear membrane reassembly

mitotic nuclear membrane organization [inference]

mitotic nuclear membrane reassembly

membrane fission

viral process [inference]

viral release from host cell

non-lytic viral release [inference]

viral budding from plasma membrane

viral budding [inference]

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

exit from host cell [inference]

viral release from host cell

non-lytic viral release [inference]

viral budding from plasma membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

endosome to lysosome transport [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

multivesicular body sorting pathway

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to lysosome transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

organic substance transport [inference]

lipid transport [inference]

sterol transport [inference]

cholesterol transport [inference]

intracellular cholesterol transport

intracellular sterol transport [inference]

intracellular cholesterol transport

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

intracellular cholesterol transport

intracellular sterol transport [inference]

intracellular cholesterol transport

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to lysosome transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

establishment of organelle localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

organelle localization [inference]

chromosome localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

establishment of organelle localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to lysosome transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway [inference]

endosome to lysosome transport via multivesicular body sorting pathway [inference]

late endosome to lysosome transport via multivesicular body sorting pathway

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

regulation of cellular localization [inference]

regulation of protein localization

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral budding via host ESCRT complex

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cytokinesis

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell division [inference]

negative regulation of cytokinesis

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral budding via host ESCRT complex

regulation of viral budding via host ESCRT complex [inference]

positive regulation of viral budding via host ESCRT complex

regulation of viral life cycle [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral budding via host ESCRT complex

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of exosomal secretion

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cytokinesis

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell division [inference]

negative regulation of cytokinesis

regulation of cell division [inference]

regulation of cytokinesis [inference]

negative regulation of cytokinesis

negative regulation of cell division [inference]

negative regulation of cytokinesis

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cytokinesis

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

regulation of cytokinesis [inference]

negative regulation of cytokinesis

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cytokinesis

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic cytokinesis checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic cytokinesis checkpoint signaling

regulation of cellular localization [inference]

regulation of protein localization

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
spindle pole	IDA	20616062
nucleus	IDA	20616062
nuclear pore	NAS	16505166
cytoplasm	IDA	11563910 15075231 20616062
lysosome	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

nuclear pore

catalytic complex [inference]

ATPase complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

late endosome membrane

bounding membrane of organelle [inference]

vacuolar membrane

endosome membrane

late endosome membrane

midbody

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
DNA clamp loader activity
protein binding	IPI	11559748 11563910 14505570 14519844 16174732 16730941 17110338 17928862 18385515 18606141 18997780 19129479 19129480 21543490 23105106 24814515 26618866 31324722 32296183 33961781 35156780 35271311 36012204
ATP binding	IMP
ATP hydrolysis activity	TAS
ATP hydrolysis activity	IMP

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a protein [inference]

ATP-dependent histone chaperone activity [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA [inference]

DNA clamp loader activity

DNA translocase activity [inference]

chromatin extrusion motor activity

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity [inference]

cohesin loader activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular carrier activity [inference]

protein carrier chaperone [inference]

histone chaperone activity [inference]

H3-H4 histone complex chaperone activity [inference]

ATP-dependent H3-H4 histone complex chaperone activity

ATP-dependent histone chaperone activity [inference]

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA [inference]

DNA clamp loader activity

DNA translocase activity [inference]

chromatin extrusion motor activity

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity [inference]

ATP-dependent protein disaggregase activity

protein-containing complex destabilizing activity [inference]

ATP-dependent protein disaggregase activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:13065

H₂O + ATP

H⁺ + phosphate + ADP

Enzyme

PMID

Disease

The Human Phenotype Ontology

Displaying entries **1 - 10** of 32 in total

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HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0000135	Hypogonadism
HP:0000252	Microcephaly
HP:0000407	Sensorineural hearing impairment
HP:0000505	Visual impairment
HP:0000519	Developmental cataract
HP:0000556	Retinal dystrophy
HP:0000750	Delayed speech and language development
HP:0001081	Cholelithiasis
HP:0001250	Seizure