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DIM1 rRNA methyltransferase and ribosome maturation factor

Summary

Gene Symbol

DIMT1

Organism

Homo sapiens (human)

External Links

NCBI Gene

27292

PubChem

27292

Alliance of Genome Resources

HGNC:30217

Annotation

Keyword

3D-structure
Methyltransferase
Nucleus
Proteomics identification
RNA-binding
Reference proteome
S-adenosyl-L-methionine
rRNA processing

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A0C4DGB1
Q9UNQ2	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase 18S rRNA dimethylase DIM1 dimethyladenosine transferase 1 homolog DIM1 dimethyladenosine transferase 1-like S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase
A8K9K8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
rRNA methylation	TAS
rRNA methylation	IMP	25851604
rRNA methylation	IBA
ribosomal small subunit biogenesis	IDA	34516797
positive regulation of rRNA processing	IMP	25851604

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular component organization or biogenesis [inference]

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

ribosomal small subunit biogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
nucleoplasm	IDA
nucleolus	IDA	25851604
nucleolus	IBA
cytosol	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex [inference]

preribosome [inference]

small-subunit processome

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
rRNA (adenine-N6,N6-)-dimethyltransferase activity	EXP	25851604
rRNA (adenine-N6,N6-)-dimethyltransferase activity	IBA
RNA binding	HDA	22658674 22681889
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	IMP	25851604

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a rRNA [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rRNA adenine N(6)-methyltransferase

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
S-adenosylmethionine-dependent methyltransferase activity
methylation
rRNA methylation
rRNA methyltransferase activity
transferase activity

Displaying **all 5** entries
InterPro
Ribosomal RNA adenine dimethylase
Ribosomal RNA adenine methylase transferase, N-terminal
Ribosomal RNA adenine methylase transferase, conserved site
Ribosomal RNA adenine methyltransferase KsgA/Erm
S-adenosyl-L-methionine-dependent methyltransferase superfamily

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements