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pre-mRNA processing factor 19

Summary

Gene Symbol

PRPF19

Organism

Homo sapiens (human)

External Links

NCBI Gene

27339

PubChem

27339

Alliance of Genome Resources

HGNC:17896

Annotation

Keyword

3D-structure
Acetylation
Cytoskeleton
DNA repair
Direct protein sequencing
Lipid droplet
Nucleus
Reference proteome
Repeat
Spliceosome
Transferase
Ubl conjugation pathway
WD repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UMS4	Nuclear matrix protein 200 PRP19/PSO4 homolog RING-type E3 ubiquitin transferase PRP19 Senescence evasion factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
DNA damage checkpoint signaling	IMP	24332808
protein polyubiquitination	IDA	11435423
spliceosomal tri-snRNP complex assembly	IDA	20595234
spliceosomal complex assembly	IMP	16332694
mRNA splicing, via spliceosome	NAS	23742842

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

protein K63-linked ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

lipid metabolic process [inference]

lipid biosynthetic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

protein K63-linked ubiquitination

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

protein K63-linked ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

protein K63-linked ubiquitination

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

protein K63-linked ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cell population proliferation [inference]

inner cell mass cell proliferation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

spliceosomal snRNP assembly [inference]

spliceosomal tri-snRNP complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

spliceosomal snRNP assembly [inference]

spliceosomal tri-snRNP complex assembly

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

spliceosomal snRNP assembly [inference]

spliceosomal tri-snRNP complex assembly

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing [inference]

positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA processing [inference]

positive regulation of mRNA splicing, via spliceosome

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
Prp19 complex	IDA	20176811
Prp19 complex	IBA
Prp19 complex	IPI	20176811
nucleus	IDA	11435423 19188445
nucleoplasm	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

Prp19 complex

nuclear protein-containing complex [inference]

DNA replication factor A complex

spliceosomal complex

U2-type spliceosomal complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

catalytic complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

ribonucleoprotein complex [inference]

spliceosomal complex

U2-type spliceosomal complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

cellular anatomical entity [inference]

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

site of DNA damage [inference]

site of double-strand break

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GO Term	Evidence Code	PMID
ubiquitin-protein transferase activity	IBA
protein binding	IPI	19188445 19633697 19641227 20176811 20467437 20595234 21536736 22365833 22569250 22961380 23022480 28514442 33961781 35271311
ubiquitin-ubiquitin ligase activity	IDA	11435423
identical protein binding	IPI	16332694
ubiquitin protein ligase activity	IDA	11435423

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity

ubiquitin-ubiquitin ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

ubiquitin-ubiquitin ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity

ubiquitin-ubiquitin ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

ubiquitin-ubiquitin ligase activity

binding [inference]

protein binding

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Pre-mRNA-processing factor 19

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
DNA repair
mRNA processing
protein K63-linked ubiquitination
protein ubiquitination
transferase activity

Displaying **all 7** entries
InterPro
Pre-mRNA-processing factor 19
Pre-mRNA-splicing factor 19
U-box domain
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily
Zinc finger, RING/FYVE/PHD-type

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	27339	Xenbase:XB-GENE-975233
Mus musculus	28000	Xenbase:XB-GENE-975233	MOUSE26166
Rattus norvegicus	246216		RATNO17635
Danio rerio	321544		DANRE07502
Pan troglodytes	451228		PANTR03049
Bos taurus	513868		BOVIN23159
Canis lupus familiaris	611552		CANLF06214
Macaca mulatta	696170		MACMU10040
Monodelphis domestica	100027038		MONDO26788
Equus caballus	100059076		HORSE05911

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements